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The Immunology Podcast

A podcast featuring conversations with immunologists from around the globe.

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A podcast featuring conversations with immunologists from around the globe.

Ep. 38: “The Urinary Bladder and Placenta” Featuring Dr. Indira Mysorekar

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Dr. Indira Mysorekar is a Professor of Medicine and Chief of Basic and Translational Research at Baylor College of Medicine. Her lab studies host–microbial interactions in the urinary bladder and the placenta. She discusses the role of the microbiome and the aging immune landscape in recurrent urinary tract infections. She also talks about her research on Zika and SARS-CoV-2 in the placenta.

Sep 27 2022

1hr 2mins

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Ep. 37: “Co-Evolution of the Human Microbiome” Featuring Drs. Ruth Ley and Sara Clasen

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Dr. Ruth Ley is Managing Director of the Max Planck Institute for Biology Tübingen and Director of the Department of Microbiome Science. Dr. Sara Clasen is a postdoctoral fellow in the same lab. Together, they're interested in the co-evolution of humans with their microbiomes. They use basic science to investigate the evolutionary history of gut microbes, how they have adapted to life inside humans, and how they affect human biology and health. More recently, they published a pre-print on the silent recognition of flagellins from human gut commensal bacteria by TLR5.

Sep 13 2022

1hr 24mins

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Ep. 36: “Engineered Immune Cell Therapies” Featuring Dr. Leonardo Ferreira

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Dr. Leonardo Ferreira is an Assistant Professor of Microbiology and Immunology at the Medical University of South Carolina. The Ferreira lab uses CARs and other engineered immune receptors to dissect how specificity, affinity, and signaling modulate the function of different T cells subsets in tolerance and immunity. He talks about how CAR Tregs could prevent transplant rejection and treat Type 1 diabetes. He also discusses mixing and matching immune cells, the freedom to pursue multiple ideas in academia, and science outreach in Bolivia

Aug 30 2022

1hr 19mins

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Ep. 35: “Inflammatory Bowel Disease” Featuring Dr. Karen Edelblum

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Dr. Karen Edelblum is an Assistant Professor of Pathology and Laboratory Medicine at Rutgers New Jersey Medical School. She discusses γδ T cells and immune-epithelial cross-talk in inflammatory bowel disease. She also talks about intravital microscopy and decorating immunology-themed cakes!

Aug 16 2022

1hr 18mins

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Ep. 34: “Immunology of the Nervous System” Featuring Dr. Jonathan Kipnis

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Dr. Jonathan Kipnis is the BJC Investigator and Alan A. and Edith L. Wolff Distinguished Professor of Pathology and Immunology at Washington University in St. Louis. His lab investigates the complex interactions between the immune and nervous systems. He talks about immune activity and surveillance in the brain, and how T cell subsets affect brain function and behavior. He also discusses the brain's immune reservoir and his lab's work on cerebrospinal fluid-regulated immune cell mobilization.

Aug 02 2022

1hr 9mins

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Ep. 33: “Academic Publishing” Featuring Dr. Mark Kaplan

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Dr. Mark Kaplan is the Chair of the Department of Microbiology and Immunology at Indiana University School of Medicine. He is currently the Editor-In-Chief for the American Association of Immunologists' journal ImmunoHorizons. Much of Dr. Kaplan’s work has focused on understanding the function of transcription factors in the development of T helper cell subsets. He talks about the role of T helper 9 cells in lung inflammation and γδ T cells in wound healing. He also discusses ImmunoHorizons and how it provides a home for solid immunological research that may otherwise remain unpublished.

Jul 19 2022

1hr 8mins

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Ep. 32: “Memory T Cell Responses” Featuring Dr. Laura Mackay

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Dr. Laura Mackay is a Professor and Laboratory Head at the Peter Doherty Institute for Infection and Immunity at the University of Melbourne. She talks about her tissue-resident memory T cell research and her ongoing collaboration with Pfizer to identify and validate new targets for cancer therapy.

Jul 05 2022

55mins

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Ep. 31: “Autoimmune Diseases and B Cell Immunity” Featuring Dr. Mark Shlomchik

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Dr. Mark Shlomchik is a UPMC Endowed Distinguished Professor and Chair of the Department of Immunology at the University of Pittsburgh. He is also a Founder and Chief Scientific Officer of BlueSphere Bio, a company working to create individualized T cell therapies for the treatment of cancer. Dr. Shlomchik’s lab focuses on systemic autoimmune diseases, long-lived B cell immunity, and immunopathogenesis. He talks about the role of toll-like receptors in lupus, how his autoimmune disease research led to potential cancer therapies, and starting a biotech company with his brother.

Jun 21 2022

1hr 8mins

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Ep. 30: “Comparative Immunology and Sharks” Featuring Dr. Hanover Matz

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Dr. Hanover Matz is a Postdoctoral Fellow at the University of Maryland, who recently completed his PhD under the supervision of Dr. Helen Dooley. He discusses why sharks may have evolved adaptive immune systems, the role of T cells, mucosal immunity, and antibodies, and working with sharks in the lab.

Jun 07 2022

1hr 5mins

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Ep. 29: “Immuno-Oncology Therapeutics” Featuring Dr. Michael Alonso

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Dr. Michael Alonso is a Scientific Co-Founder, and Vice President of Immunology & Pharmacology at Bolt Biotherapeutics, a biotechnology company developing immunotherapies that activate myeloid cells. He discusses targeting tumors by covering them in "eat me" signals, considerations for moving drugs into the clinic, and building teams in biotech.

May 24 2022

1hr 10mins

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“AAI 2022: Treg Modulation” Featuring Dr. Alice Long

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Dr. Alice Long is an Associate Member of the Center for Translational Immunology at Benaroya Research Institute at Virginia Mason. The Long lab is focused on understanding how tolerance is lost in autoimmunity, specifically as it related to type 1 diabetes. Dr. Long discusses the work she presented at the American Association of Immunologists’ annual meeting, IMMUNOLOGY2022, on CD8 T cell exhaustion and Treg modulation.

May 10 2022

25mins

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“AAI 2022: Epithelial Immunity” Featuring Dr. Shruti Naik

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Dr. Shruti Naik is an Assistant Professor of Biological Sciences at New York University Langone Medical Center. She studies immunity in the epithelial tissues that line our body to understand how environmental stimuli collaborate with genetic factors to influence health and drive disease at these interfaces. She discusses the work she's presenting at the American Association of Immunologists' annual meeting, IMMUNOLOGY2022, on trained immunity and immune-epithelial crosstalk in tissue repair.

May 08 2022

31mins

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“AAI 2022: Peritoneal Macrophages” Featuring Dr. Gwendalyn Randolph

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Dr. Gwendalyn Randolph is the Emil R. Unanue Distinguished Professor in the Department of Immunology and Pathology at Washington University in St. Louis. Research in her lab integrates the study of monocytes, monocyte-derived cells, and dendritic cells with vascular and lymphatic vessel biology. She discusses the work she's presenting at the American Association of Immunologists' annual meeting, IMMUNOLOGY2022, on the diversity, function, and mysteries of peritoneal macrophages.

May 06 2022

36mins

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Ep. 28: “Exploring Regulatory T Cells” Featuring Dr. Michael Rosenblum

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Dr. Michael Rosenblum is a Professor of Dermatology at the University of California, San Francisco. His lab seeks to to understand how immune responses are regulated in tissues and how this knowledge can be exploited for therapeutic benefit. They are currently investigating how Tregs control immune responses in tissues, as well as their “alternative” functions. He talks about early-life inflammation and type 2 helper T cells in the skin, and how Tregs can be manipulated to target autoimmune diseases and cancer.

Apr 26 2022

1hr 11mins

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Ep. 27: “AAI 2022: Building on the Past to Meet the Moment” Featuring Dr. Gary Koretzky

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Dr. Gary Koretzky is President of the American Association of Immunologists, Vice Provost for Academic Integration at Cornell University, Professor of Medicine at Weill Cornell Medicine, and Director of the Cornell Center for Immunology. He talks about how he began his career in immunology, using science to guide Cornell's response to COVID-19, and what to expect at AAI's Immunology 2022 meeting taking place May 6-10th.

Apr 12 2022

1hr 19mins

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Ep. 26: “Viruses and Glycoproteins” Featuring Dr. Florian Krammer

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Dr. Florian Krammer is a Professor of Vaccinology at Icahn School of Medicine at Mount Sinai. His lab focuses on understanding broadly-reactive immune responses against the surface glycoproteins of RNA viruses such as influenza, with the goal to develop better vaccines and novel therapeutics. He talks about his lab's shift to COVID-19 research, strategies for vaccine development, and how we can prepare for future pandemics.

Mar 29 2022

1hr 8mins

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Ep. 25: “Immunology and Industry” Featuring Drs. Andy Kokaji and Hannah Lee

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Dr. Andy Kokaji is a Senior Director of Immunology, and Dr. Hannah Lee is a Senior Director of Product Management, at STEMCELL Technologies. They discuss their career paths and how they develop and commercialize products to support scientists worldwide.

Mar 15 2022

1hr 6mins

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Ep. 24: “Autoimmune Disease” Featuring Dr. Jennifer Gommerman

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Dr. Jennifer Gommerman is a Professor of Immunology at the University of Toronto. Her team has uncovered a novel gut-brain axis that regulates neuroinflammation and is examining the role of B lymphocytes in Multiple Sclerosis (MS) patients and in animal models of MS. More recently, she has been studying the antibody response to SARS-CoV-2 in saliva samples from patients with COVID-19. She talks about the role of gut-derived plasma cells in multiple sclerosis, and how salivary immunoglobulin A can protect against breakthrough COVID-19 infections.

Mar 01 2022

1hr 20mins

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Ep. 23: “Dendritic Cells and the Immune System” Featuring Dr. Caetano Reis e Sousa

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Dr. Caetano Reis e Sousa is the Assistant Research Director and Senior Group Leader at the Francis Crick Institute. His lab studies the molecular pathways that trigger dendritic cells into action. He talks about the mechanisms of dendritic cell cross-presentation, RNA interference, and dendritic cell progenitors in influenza.

Feb 15 2022

1hr 6mins

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Ep. 22: “Maternal Immune Cells” Featuring Dr. Francesco Colucci

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Dr. Francesco Colucci is a Wellcome Investigator and Professor of Immunology at the University of Cambridge. His research focuses on natural killer (NK) and other innate lymphoid cells, as well as immunogenetics. He talks about uterine NK cells and their education, and falling in love with research as a physician.

Feb 01 2022

1hr 8mins

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