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Health & Fitness
Medicine
Science

Gut podcast

Updated 5 days ago

Health & Fitness
Medicine
Science
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Gut is a leading international journal in gastroenterology and has an established reputation for publishing first class clinical research of the alimentary tract, the liver, biliary tree and pancreas. Gut delivers up-to-date, authoritative, clinically oriented coverage of all areas in gastroenterology. Regular features include articles by leading authorities, reports on the latest treatments for diseases, reviews and commentaries.Subscribers to Gut also receive Frontline Gastroenterology (FG). Gut has increased its position ranking in the category of the Gastroenterology and Hepatology from 3rd to 2nd, with a new impact factor of 14.921.* The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

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Gut is a leading international journal in gastroenterology and has an established reputation for publishing first class clinical research of the alimentary tract, the liver, biliary tree and pancreas. Gut delivers up-to-date, authoritative, clinically oriented coverage of all areas in gastroenterology. Regular features include articles by leading authorities, reports on the latest treatments for diseases, reviews and commentaries.Subscribers to Gut also receive Frontline Gastroenterology (FG). Gut has increased its position ranking in the category of the Gastroenterology and Hepatology from 3rd to 2nd, with a new impact factor of 14.921.* The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

iTunes Ratings

4 Ratings
Average Ratings
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1
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0

iTunes Ratings

4 Ratings
Average Ratings
2
1
1
0
0

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Cover image of Gut podcast

Gut podcast

Updated 5 days ago

Read more

Gut is a leading international journal in gastroenterology and has an established reputation for publishing first class clinical research of the alimentary tract, the liver, biliary tree and pancreas. Gut delivers up-to-date, authoritative, clinically oriented coverage of all areas in gastroenterology. Regular features include articles by leading authorities, reports on the latest treatments for diseases, reviews and commentaries.Subscribers to Gut also receive Frontline Gastroenterology (FG). Gut has increased its position ranking in the category of the Gastroenterology and Hepatology from 3rd to 2nd, with a new impact factor of 14.921.* The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Rank #1: A systematic review of isolated colonic Crohn's disease: the third IBD?

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In this podcast Mairi McLean talks to Professor Jon Rhodes about his recently published paper "Recent advances in clinical practice: a systematic review of isolated colonic Crohn's disease: the third IBD?"

Full paper >> http://gut.bmj.com/content/66/2/362

Feb 27 2017

17mins

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Rank #2: Bifidobacterium and gastrointestinal inflammation

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Liam O’Mahony (Swiss Institute of Allergy and Asthma Research) talks to Mairi McLean (senior clinical lecturer and consultant in gastroenterology at the University of Aberdeen) about his paper looking at Bifidobacterium infantis’s interaction with T cells, and the bacterium’s potential to protect against gastrointestinal inflammation.

See also:

Bifidobacterium infantis 35624 administration induces Foxp3 T regulatory cells in human peripheral blood: potential role for myeloid and plasmacytoid dendritic cells (http://tinyurl.com/b6xnnsx)

Feb 21 2013

16mins

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Rank #3: Antibiotics as deep modulators of gut microbiota: between good and evil.

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In this podcast Mairi McLean interviews Dr Gianluca Ianiro about the editors choice paper "Antibiotics as deep modulators of gut microbiota: between good and evil."

Full paper >> http://gut.bmj.com/content/65/11/1906.full?sid=4929814b-b6f1-43d2-9af1-964357aa664c

Jan 04 2017

17mins

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Rank #4: Live birth and adverse birth outcomes in women with ulcerative colitis and Crohn's disease

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In this podcast Dr Mairi McLean talks to Dr Sonia Friedman about the May editors choice paper "Live birth and adverse birth outcomes in women with ulcerative colitis and Crohn's disease receiving assisted reproduction: a 20-year nationwide cohort study".

Full text > http://gut.bmj.com/content/65/5/767.full

Jun 17 2016

13mins

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Rank #5: Amniotic stem cell treament for necrotic enterocolitis

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Necrotising enterocolitis (NEC) remains one of the primary causes of morbidity and mortality in neonates and alternative strategies are needed. Stem cells have become a therapeutic option for other intestinal diseases, which share some features with NEC.

Along with colleagues, Simon Eaton and Paolo De Coppi, both from University College London Institute of Child Health, have tested the hypothesis that amniotic fluid stem (AFS) cells exerted a beneficial effect in a neonatal rat model of NEC.

Mairi McLean discusses their findings with them.

Read the full paper:

Amniotic fluid stem cells improve survival and enhance repair of damaged intestine in necrotising enterocolitis via a COX-2 dependent mechanism http://goo.gl/EFUuN0

Feb 21 2014

24mins

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Rank #6: Characterisation of faecal protease activity in irritable bowel syndrome with diarrhoea

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Mairi McLean talks to Robin Spiller, NIHR Nottingham Digestive Diseases Biomedical Research Unit, and David Tooth, School of Biomedical Sciences, University of Nottingham, about their paper: Characterisation of faecal protease activity in irritable bowel syndrome with diarrhoea: origin and effect of gut transit.

Read the full article: http://goo.gl/0OIP34

Jun 09 2014

20mins

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Rank #7: Surveillance endoscopy is associated with improved outcomes of oesophageal adenocarcinoma

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In this track Mairi McLean talks to Hasim El-Serag about the recent paper "Surveillance endoscopy is associated with improved outcomes of oesophagealadenocarcinoma detected in patients with Barrett's oesophagus."

Sep 22 2016

27mins

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Rank #8: PUFAS and neoplasms

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Mairi McLean, Gut education editor, talks to Professor Mark Hull, Leeds Institute of Molecular Medicine, about his research into the action of polyunsaturated fatty acids on the formation of neoplams.

See also:

Omega-3 polyunsaturated fatty acids for the treatment and prevention of colorectal cancer (http://tinyurl.com/a7q8co4)

Feb 21 2013

23mins

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Rank #9: Gut podcast: Treatment of pancreatic fibrosis with siRNA

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Fibrosis associated with chronic pancreatitis is an irreversible lesion that can disrupt pancreatic exocrine and endocrine function. Currently, there are no approved treatments for this disease.

In this podcast Mairi McLean, Gut education editor, talks to Professor Yoshiro Niitsu from Sapporo Medical University School of Medicine about his manuscript about the potential for therapeutic use of siRNA in the treatment of pancreatic fibrosis.

Read the full research online:

http://gut.bmj.com/content/62/9/1328

Oct 22 2013

13mins

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Rank #10: AIEC pathobiont instigates chronic colitis in susceptible hosts by altering microbiota composition

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Inflammatory bowel disease is driven by a seemingly aberrant immune response to the gut microbiota with disease development dictated by genetics and environmental factors. A model exemplifying this notion is work by Andrew Gewirtz, Center for Inflammation, Immunity, & Infection, Georgia State University, and colleagues, demonstrating that colonisation of adherent-invasive Escherichia coli (AIEC) during microbiota acquisition drove chronic colitis in mice lacking the flagellin receptor TLR5 (T5KO).

They have now published a paper in Gut hypothesising that AIEC instigates chronic inflammation by increasing microbial lipopolysaccharide and flagellin levels, and investigating how AIEC colonisation might instigate colitis in T5KO mice.

Mairi McLean talks to Dr Gerwitz about their findings.

Read the full paper (for free): http://gut.bmj.com/content/63/7/1069.full

Aug 21 2014

15mins

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Rank #11: Update on basic and clinical aspects of eosinophilic oesophagitis

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The identification of a distinct syndrome, designated eosinophilic oesophagitis (EoE), with its own clinical and histopathological characteristics, was first described in the early 1990s. Meanwhile intense research has uncovered many molecular, immunological and clinical aspects of this chronic-inflammatory disorder.

In this podcast, Mairi McLean talks to Professor Alex Straumann, Swiss EoE Clinic and EoE Research Network, about the basic and clinical insights of EoE gathered during the last few years.

Read Professor Straumann's update on the topic:

http://goo.gl/0B6h14

Sep 25 2014

25mins

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Rank #12: Besifovir versus entecavir in Asian patients with chronic hepatitis B

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Despite the success of hepatitis B virus vaccination in preventing new infection in endemic areas, chronic hepatitis B still poses a heavy burden globally. There are approximately 350 million carriers in the world, with an estimated 60 000 persons dying annually of hepatitis B-related cirrhosis and hepatocellular carcinoma.

In a study recent published in Gut, Professor Man-Fung Yuen, Department of Medicine, The University of Hong Kong, and colleagues, report the results of viral suppression and safety of two doses of besifovir, with entecavir as a comparator in treatment-naive subjects for 48 weeks.

He talks to Mairi McLean about the findings.

Read the full paper:
Phase IIb multicentred randomised trial of besifovir (LB80380) versus entecavir in Asian patients with chronic hepatitis B http://gut.bmj.com/content/63/6/996.full

Aug 15 2014

9mins

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Rank #13: mTNF reverse signalling induced by TNFα antagonists involves a GDF-1 dependent pathway

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Mairi McLean talks to Philip Rosenstiel, Institute of Clinical Molecular Biology, Christian-Albrechts University, Kiel, and Stefan Schreiber, University Hospital Schleswig-Holstein, Kiel, about their paper: mTNF reverse signalling induced by TNFα antagonists involves a GDF-1 dependent pathway: implications for Crohn’s disease http://bit.ly/11FU0Qw.

Apr 24 2013

26mins

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Rank #14: BMP-9 interferes with liver regeneration and promotes liver fibrosis

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In this episode Mairi McLean, Education Editor for Gut, talks to Dr Katja Breitkopf-Heinlein, Medical Faculty Mannheim, Heidelberg University, about her recently published paper "BMP-9 interferes with liver regeneration and promotes liver fibrosis".

Full paper >> http://gut.bmj.com/content/66/5/939

May 31 2017

16mins

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Rank #15: Recent advances in clinical practice challenges and opportunities in the management of obesity

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Mairi McLean talks to Andres Acosta and Barham K Abu Dayyeh, both Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, about their review on the management of obesity.

Read the full paper: http://goo.gl/V37xaq

Apr 29 2014

23mins

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Rank #16: Bowel cancer screening in England

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Before the UK national bowel cancer screening programmes were implemented, a pilot was set-up in England to see if results from randomised controlled trials could be replicated in the general population. Gut has recently published findings from the third round of this.

Co-author David Weller, Centre for Population Health Sciences–General Practice, University of Edinburgh, UK, talks to Gut’s associate editor William Grady about effectiveness of screening, uptake and its link to ethnicity, and the potential of different methods.

See also:

Performance measures in three rounds of the English bowel cancer screening pilot (http://tinyurl.com/afyj365)

Feb 21 2013

20mins

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Rank #17: British Society of Gastroenterology guidelines on diagnosing and managing Barrett's oesophagus

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Gut's education editor Mairi McLean discusses highlights from the guidelines on the diagnosis and management of Barrett's oesophagus with authors Rebecca Fitzgerald and Massimiliano di Pietro, both from the MRC Cancer Unit, University of Cambridge.

Read the full paper here: http://bit.ly/1kkPkVW

Jan 31 2014

24mins

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Rank #18: Cancer treatment induced gastrointestinal symptoms

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In the UK chronic gastrointestinal symptoms after cancer therapies have a similar impact as IBD. However, in contrast to patients with IBD, most of these patients won’t see a gastroenterologist. In this month’s Gut Editor’s Choice the causes of these side effects of cancer treatment are discussed, as well as the benefits of investigation and treatment.

In this podcast Mairi McLean, senior clinical lecturer and consultant in gastroenterology at the University of Aberdeen talks to some key stakeholders in this issue:

Professor Sir Mike Richards, national clinical director for cancer and end of life care, Department of Health

Jane Maher, chief medical officer for McMillian Cancer Support

Jon Rhodes, professor of gastroenterology and president of the British Society of Gastroenterology

Jervoise Andeyev, consultant gastroenterologist in pelvic radiation disease at the Royal Marsden NHS Trust, London

See also:

Practice guidance on the management of acute and chronic gastrointestinal problems arising as a result of treatment for cancer (http://tinyurl.com/a6krvl8)

Feb 21 2013

40mins

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Rank #19: Endoscopic improvement of mucosal lesions in patients with ileocolonic Crohn’s disease

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Mairi McLean, Gut’s education editor, talks to Xavier Hébuterne, Department of Gastroenterology and Nutrition, Archet Hospital, Nice, and Jean-Frédéric Colombel, Universite Lille Nord de France, about their paper: Endoscopic improvement of mucosal lesions in patients with moderate to severe ileocolonic Crohn’s disease following treatment with certolizumab pegol http://bit.ly/10dtab8.

Apr 24 2013

23mins

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Rank #20: Intra-tumoural stroma as a predictor of survival in patients with gastric cancer

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Mairi McLean talks to Patrick Tan, associate professor, Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School Singapore, and Heike Grabsch, Pathology and Tumour Biology, Leeds Institute of Molecular Medicine, University of Leeds, about their genomic meta-analysis to identify predictors of survival in patients with gastric cancer.

See also:

Comprehensive genomic meta-analysis identifies intra-tumoural stroma as a predictor of survival in patients with gastric cancer http://goo.gl/Rw8lx6

Aug 02 2013

17mins

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