Exploring Pathogenic Virus Diseases with Professor St. Patrick Reid
Finding Genius Podcast
Dr. Reid specializes in host pathogen interactions studies such as investigating the chikungunya virus infection and Ebola virus microbiology. A returning guest, he and Richard discuss all things virus in this episode as Dr. Reid will contribute to Richard's upcoming book on viruses. Their conversation covers Why it's significant that all life forms have associated viruses, including ancient bacteria discovered recently in glacial inlands that have phages (viruses that infect bacteria); What implications exciting virus discoveries may hold, such as the giant Mimivirus, which may prove an evolutionary bridge; and How we can investigate virus characteristics like means of entry and coopting of cellular machinery to better understand means of replication and evolutionary success as well as how cellular machinery works in the first place. St. Patrick Reid is an assistant professor in the Pathology and Microbiology Department in the University Of Nebraska Medical Center College Of Medicine. In a previous podcast, he and Richard discuss chikungunya diagnosis and pathology and Ebola virus symptoms and behavior. He begins this discussion explaining his journey into the field, which includes exciting postdoc work in France on Ebola. Now his researcher involves host pathogen interactions and he's particularly interested in different host proteins a virus has to recruit to replicate. The conversation takes a turn into exploring what scientists have assumed about viruses compared to recent discoveries that may take that knowledge in new directions. For example, he talks about ancient phage discoveries in glacial bacteria and phage-bacteria coevolution. He describes an interest in how viruses that infect bacteria allow those bacteria to live in a community of other bacterium. The viruses actually play a role in enabling those bacteria to survive. He discusses numerous other virus characteristics and implications, from DNA versus RNA viruses and what that dictates regarding habits like latency. He also addresses when that understanding changes with new discoveries, such as finding Ebola virus in chimps months after infection. They also talk a little virus philosophy and cover topics like what enables virus entry into cells and how tropism works. For more about Dr. Reid and his work, see his website at the university, unmc.edu/pathology/faculty/bios/reid.html, and follow him on Twitter as @StPatrickReid3. Available on Apple Podcasts: apple.co/2Os0myK
The Chikungunya Virus Infection and Other Host-Pathogen Interaction Examples with St. Patrick Reid
Finding Genius Podcast
What exactly does a virus do to invade our bodies? Scientist St. Patrick Reid addresses the mechanics through specific virus pathologies. He addresses how viruses use proteins to undercut the immune system and ensure replication, how the chikungunya virus infection has become more prevalent and often leaves chronic symptoms, and why these lasting effects from this RNA virus are especially puzzling and how scientists approach such questions. St Patrick Reid is an assistant professor in the Department of Pathology and Microbiology at the University of Nebraska. He focuses on the virology of proteins encoded by highly pathogenic viruses like the chikungunya virus infection. He explains what this means by describing his graduate and early career studies on Ebola and other host-pathogen interaction examples. Ebola is able to invade an organisms by encoding for proteins that block the immune system from responding. This gives the virus enough time to amplify itself and replicate. When the body is finally able to react, the virus is so pervasive it over reacts, often unleashing a dangerous over-response; in fact, this is what happens with COVID-19. Dr. Reid than describes the history of the chikungunya virus infection and how it has made its way from one part of the world to another, including South America and the southern United States. Transmitted by mosquitoes, it often results in a debilitating arthritis that can last for years and scientists don't understand how or why. In fact, that's one of his areas of research, to understand its pathology. As an RNA virus, it does not invade the nucleus and change the genome. He explains some possible theories and his own approach to solving this mystery. He also discusses his thoughts on COVID-19 from his protein-focused research and describes the magnanimous ways researchers are working together across the world to find ways to combat its effects. The best way to keep an eye on his work and learn more include following him on Twitter as @StPatrickReid3 as well as reviewing his university lab web page at unmc.edu/pathology-research/microbiology/virology/reidlab. Available on Apple Podcasts: apple.co/2Os0myK
In this episode, we're delighted to be interviewing ex new york hedge fund trader Patrick Reid. We discuss 'king dollar' and how it influences equity prices, Patrick's swing trading techniques and the risk management principles of ‘braveheart’, a trader who made $100million. Patrick now manages Adamis Principle a company set up to help educate and mentor traders at all levels. They are also currently seeding students into the best Prop desks in London with full funding.Want further Opto insights? Check out our daily newsletter: https://www.cmcmarkets.com/en-gb/opto/newsletter
Starring Patrick Reid @ZephyrBlaze456 on Twitter and @ZephyrBlaze#2645 on Discord. Also guesting is Ms. Debbie Reid, Patrick’s mom. We discuss setting and achieving Patrick's goal of becoming an Eagle Scout as well as his role with the network.
Leading Age Services Australia national chief executive Patrick Reid encouraging families to discuss the care needs of ageing relatives in early 2016 and learn more about Australia’s age-services system.