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Blood Podcast

The Blood Podcast summarizes content recently published in Blood the most cited peer-reviewed publication in the field of hematology.

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AIHA during pregnancy, rapid immune tolerance induction in severe hemophilia A, and aging changes control of HSC proliferation

AIHA during pregnancy, rapid immune tolerance induction in severe hemophilia A, and aging changes control of HSC proliferation

In this week’s episode we will review treatment and outcomes for patients with autoimmune hemolytic anemia during pregna... Read more

20 Apr 2023

17mins

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Review Series on Classical Myeloproliferative Neoplasms

Review Series on Classical Myeloproliferative Neoplasms

In this episode Associate Editor, Dr. Mario Cazzola discusses the review series on Classical Myeloproliferative Neoplasm... Read more

20 Apr 2023

22mins

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Factor H variants in paroxysmal nocturnal hemoglobinuria, the role of factor XII in SCD-related thrombosis, and clinical features of therapy-related NPM1-mutated AML

Factor H variants in paroxysmal nocturnal hemoglobinuria, the role of factor XII in SCD-related thrombosis, and clinical features of therapy-related NPM1-mutated AML

In this week’s episode, we’ll learn how rare germline genetic variants in complement factor H (CFH) affect the course of... Read more

14 Apr 2023

22mins

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Lenalidomide and genetic profiling in myeloma, T-cell immunotherapy upregulates AML cell MHC-class II, and young fecal microbiota rejuvenate HSCs

Lenalidomide and genetic profiling in myeloma, T-cell immunotherapy upregulates AML cell MHC-class II, and young fecal microbiota rejuvenate HSCs

In this week’s episode we will review optimizing the value of post-transplant lenalidomide maintenance in multiple myelo... Read more

6 Apr 2023

16mins

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HLA-E-restricted immune response in EBV infection, the role of NRX-0492 in CLL, and NSAIDs for bone marrow failure in Ghosal Hematodiaphyseal Dysplasia

HLA-E-restricted immune response in EBV infection, the role of NRX-0492 in CLL, and NSAIDs for bone marrow failure in Ghosal Hematodiaphyseal Dysplasia

In this week’s episode we’ll learn how HLA-E-restricted immune responses help control Epstein-Barr virus infection, disc... Read more

30 Mar 2023

23mins

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Review Series on Germ Line Predisposition to Hematologic Malignancy

Review Series on Germ Line Predisposition to Hematologic Malignancy

In this bonus episode Associate Editor, Dr. Mario Cazzola discusses the review series on Germline predisposition to hema... Read more

30 Mar 2023

33mins

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Anti-malaria benefit of hydroxyurea in SCA, IL-22 in the treatment in lower GI acute GVHD, and FLT3-ITD changes depend on context in AML

Anti-malaria benefit of hydroxyurea in SCA, IL-22 in the treatment in lower GI acute GVHD, and FLT3-ITD changes depend on context in AML

In this week’s episode we will review a study in sub-Saharan Africa where treatment of sickle cell anemia with hydroxyur... Read more

23 Mar 2023

18mins

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Single-cell genotyping of MDS/CMML clonal output, VTE risk in diffuse glioma, and Del(1p32) is an adverse prognostic factor in myeloma

Single-cell genotyping of MDS/CMML clonal output, VTE risk in diffuse glioma, and Del(1p32) is an adverse prognostic factor in myeloma

In this week’s episode we’ll discuss how azacytidine therapy influences the contributions of mutated HSC clones to hemat... Read more

16 Mar 2023

20mins

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RUNX1 isoform imbalance drives ML-DS, VWF-binding RNA aptamer for hemophilia A treatment, and EZH1/2 inhibitor valemetostat in relapsed/refractory ATL

RUNX1 isoform imbalance drives ML-DS, VWF-binding RNA aptamer for hemophilia A treatment, and EZH1/2 inhibitor valemetostat in relapsed/refractory ATL

In this week’s episode we will review an imbalance among RUNX1 isoforms is key to the pathogenesis of trisomy 21-associa... Read more

9 Mar 2023

17mins

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Phase 3 trial of leniolisib in activated PI3Kδ syndrome, dabrafenib plus trametinib in relapsed/refractory hairy cell leukemia, and TγδLGL leukemia as a more symptomatic subset of leukemia

Phase 3 trial of leniolisib in activated PI3Kδ syndrome, dabrafenib plus trametinib in relapsed/refractory hairy cell leukemia, and TγδLGL leukemia as a more symptomatic subset of leukemia

In this week’s episode, we’ll discuss the findings from a phase 3 trial of PI3Kδ inhibitor leniolisib in activated PI3Kd... Read more

2 Mar 2023

21mins

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