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Thorax podcast

Updated 4 days ago

Health & Fitness
Medicine
Science
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Thorax, the official journal of the British Thoracic Society, publishes influential clinical and experimental research in respiratory medicine, paediatrics, immunology, pharmacology, pathology, and surgery. The focus is on work that advances scientific understanding and impacts clinical practice. http://thorax.bmj.com/* The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

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Thorax, the official journal of the British Thoracic Society, publishes influential clinical and experimental research in respiratory medicine, paediatrics, immunology, pharmacology, pathology, and surgery. The focus is on work that advances scientific understanding and impacts clinical practice. http://thorax.bmj.com/* The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

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Cover image of Thorax podcast

Thorax podcast

Updated 4 days ago

Read more

Thorax, the official journal of the British Thoracic Society, publishes influential clinical and experimental research in respiratory medicine, paediatrics, immunology, pharmacology, pathology, and surgery. The focus is on work that advances scientific understanding and impacts clinical practice. http://thorax.bmj.com/* The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Rank #1: Journal club: Efficacy of a tyrosine kinase inhibitor in idiopathic pulmonary fibrosis

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Only one treatment is licensed for idiopathic pulmonary fibrosis and this only in Europe. Luca Richeldi (Center for Rare Lung Diseases, University of Modena, Italy) describes his phase 2 trial of a tyrosine kinase inhibitor to see if it could be safely and effectively used in patients with the disease. Dr Richeldi’s research was published in the New England Journal of Medicine.

See also:

http://www.nejm.org/doi/full/10.1056/NEJMoa1103690

Feb 13 2013

6mins

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Rank #2: Journal Club: Lung protective mechanical ventilation

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Jennifer Quint (Thorax’s journal club editor) talks to Dale Needham (associate professor of medicine, Johns Hopkins University School of Medicine) about his paper recently published in the BMJ:

See also:

http://www.bmj.com/content/344/bmj.e2124

Feb 13 2013

9mins

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Rank #3: Journal club: Detecting COPD through lung cancer screening

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Jennifer Quint (Thorax’s Journal Club editor) talks to Onno Mets (Department of Radiology, University Medical Centre Utrecht) about his paper recently published in JAMA:

http://jama.jamanetwork.com/article.aspx?articleid=1104554

Feb 13 2013

3mins

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Rank #4: Journal Club: CPAP for the metabolic syndrome in patients with obstructive sleep apnea

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Obstructive sleep apnea is associated with an increased prevalence of the metabolic syndrome and its components. Professor SK Sharma (head of the Department of Medicine, All India Institute of Medical Sciences) has investigated whether treatment of obstructive sleep apnea syndrome with continuous positive airway pressure (CPAP) would modify these outcomes. Jennifer Quint (Thorax’s Journal Club editor) speaks to him about his results recently published in The New England Journal of Medicine.

See also:

http://www.nejm.org/doi/full/10.1056/NEJMoa1103944

Feb 13 2013

8mins

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Rank #5: Journal club: Airway bypass for emphysema

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Jennifer Quint (Thorax’s journal club editor) talks to Pallav Shah (a respiratory physician at the Royal Brompton Hospital, UK) about his trial of airway bypass for patients with severe emphysema, recently published in the Lancet.

Dr Shah explains the procedure and how effective it was.

See also:

http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2811%2961050-7/abstract

Feb 13 2013

5mins

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Rank #6: Journal club: Cytisine for smoking cessation

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Many treatments available for smoking cessation are unaffordable for the majority of smokers, however cytisine is one exception. Jennifer Quint (Thorax’s journal club editor) talks to Robert West (Department of Epidemiology and Public Health, University College London) about the mechanism of the drug and his research into its efficacy and cost-effectiveness. Professor West’s trial was recently published in the New England Journal of Medicine.

See also:

http://www.nejm.org/doi/full/10.1056/NEJMoa1102035

Feb 13 2013

10mins

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Rank #7: Air Pollution affects Lung Cancer Survival

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Patients exposed to air pollution after diagnosis of lung cancer have shorter survival, in particular those patients with early-stage non-small cell cancers (specially adenocarcinomas), according to a study published by Thorax and conducted by researchers from the Department of Preventive Medicine, University of Southern California.

The first study of this kind was based on a population of over 300 thousand patients with newly diagnosed lung cancer over more than two decades.

In this podcast, Dr Jaime Hart, from the Channing Division of Network Medicine, Brigham and Women’s Hospital and Harvard Medical School and author of the Thorax editorial about this study, tells Dr Jennifer Quint the details of this study and its impact on how air pollution is considered by general population.

Read the original article ’Air pollution affects lung cancer survival’, which corresponding author is Dr Sandrah P Eckel, here:
http://thorax.bmj.com/content/early/2016/06/22/thoraxjnl-2015-207927.full.

The editorial is available here:
http://thorax.bmj.com/content/early/2016/07/20/thoraxjnl-2016-208967.full.

Jul 25 2016

5mins

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Rank #8: Journal Club: Outcomes after thoracoscopic versus open lobectomy

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Jennifer Quint, Thorax’s Journal Club editor, talks to Subroto Paul, Division of Thorasic Surgery at New York Presbrytarian Hospital System, about his study comparing short-term postoperative outcomes following open and thoracoscopic lobectomy.

See also:

http://www.ncbi.nlm.nih.gov/pubmed/22826474

http://thorax.bmj.com/content/early/2012/08/23/thoraxjnl-2012-202521.full

Feb 13 2013

8mins

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Rank #9: Journal Club: Predicting survival in resected non-small-cell lung cancer

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Jennifer Quint, Thorax’s Journal Club editor, talks to David Jablons, University of California San Francisco, and consultant for Life Technologies, about his assay to predict survival in resected non-squamous, non-small-cell lung cancer.

See also:

http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2811%2961941-7/abstract

Feb 13 2013

8mins

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Rank #10: Air pollution and the London low emission zone

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In this podcast Dr Ian Mudway talks to Dr Elizabeth Batalla-Duran about his recent paper in Plos-One entitled "Effects of air pollution and introduction of the London low emission zone on the prevalence of respiratory and allergic symptoms on the school children of East London".

Nov 17 2015

14mins

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Rank #11: E-cigarette use and smoking in early adolescence

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In this podcast Dr Elizabeth Batalla-Duran talks to Dr Adam Leventhal from the University Southern California about his paper "Association of Electronic Cigarette Use With Initiation of Combustible Tobacco Product Smoking in Early Adolescence" recently published in JAMA.

Sep 30 2015

14mins

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Rank #12: Long-term experience with rituximab in anti-synthetase syndrome-related interstitial lung disease

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In this podcast Dr Janice Higginson talks to Dr Helena Anderson from Oslo University Hospital about her recent paper published in Rheumatology. The paper is a retrospective review of research done into rituximab's effect on the rare Antisynthetase Syndrome.

Sep 29 2015

9mins

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Rank #13: Pneumococcal vaccination for welders

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Thorax deputy editor Paul Cullinan talks to David Coggon, MRC Lifecourse Epidemiology Unit, University of Southampton, about pneumococcal vaccination for welders.

Read the full article: http://goo.gl/p3qN8s

Oct 01 2014

9mins

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Rank #14: The genomic origins of asthma

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Ian Pavord talks to Scott Weiss, Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, about his review on the genomic origins of asthma, which considers several areas where environmental exposures, genomics, development and asthma occurrence overlap.

Read the full review: http://goo.gl/KctouZ

Jul 08 2014

14mins

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Rank #15: The promise of translational and personalised approaches for paediatric obstructive sleep apnoea

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Obstructive sleep apnoea (OSA) can result in significant morbidities including the cardiovascular, metabolic and neurocognitive systems. While great advances have been made in sleep medicine research in the past decades, there are still wide gaps in our knowledge concerning the exact underlying pathophysiological mechanisms of OSA and consequences.

A recent review in Thorax discusses the recent exciting discoveries in genotype-phenotype interactions, epigenetics, genomics and proteomics related to OSA. Thorax editor Andy Bush talks to co-author David Gozal, professor in the Department of Pediatrics, The University of Chicago, about the highlights.

Read the full paper:

The promise of translational and personalised approaches for paediatric obstructive sleep apnoea: an ‘Omics’ perspective http://goo.gl/fKf28O

May 14 2014

19mins

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