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Medical Breakthroughs from Penn Medicine

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Medicine
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Medical Breakthroughs features the newest medical advancements in the areas of oncology, cardiology, neurosciences, orthopedics, and genetics featuring America’s leading physicians and medical researchers from Penn Medicine.In Partnership with

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Medical Breakthroughs features the newest medical advancements in the areas of oncology, cardiology, neurosciences, orthopedics, and genetics featuring America’s leading physicians and medical researchers from Penn Medicine.In Partnership with

iTunes Ratings

5 Ratings
Average Ratings
4
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0
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iTunes Ratings

5 Ratings
Average Ratings
4
1
0
0
0
Cover image of Medical Breakthroughs from Penn Medicine

Medical Breakthroughs from Penn Medicine

Latest release on May 20, 2020

The Best Episodes Ranked Using User Listens

Updated by OwlTail 9 days ago

Rank #1: Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration

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Guest: Andrew Haas, MD, PhD
Host: Lee Freedman, MD

Until recently, bronchoscopy has involved using cameras with CT guidance to determine abnormalities along the airway and lymph nodes. How is ultrasound now being used for bronchoscopic needle biopsies? What are other novel therapeutic applications for endobronchial ultrasound-guided transbronchial needle aspiration? Dr. Andrew Haas, assistant professor of medicine in the pulmonary, allergy and critical care division at the University of Pennsylvania Medical Center, discusses the diagnostic and therapeutic uses of ultrasound-guided bronchoscopy. Dr. Lee Freedman hosts.

Dec 05 2008

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Rank #2: Novel Approaches to Bone Marrow and Stem Cell Transplant

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Guest: David Porter, MD
Host: Lee Freedman, MD

The conventional bone marrow transplant procedure can have many side effects, and the traditional procedure can be especially risky for older patients or other patients with comorbidities. How are novel approaches of bone marrow and stem cell transplantation attempting to limit the toxicity and improve the safety of the procedure? Our guest, Dr. David Porter, professor of medicine and director of stem cell transplantation at Penn Medicine, discusses how using an immunosuppresive approach to the bone marrow transplant procedure may benefit a greater number of patients. Hosted by Dr. Lee Freedman.

Produced in Cooperation with

Jun 11 2009

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Rank #3: Innovations in Vascular Surgery

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Host: Lee Freedman, MD

How does surgery and stenting for carotid lesions help prevent stroke? What are the latest approaches, clinical trials, and philosophy for dialysis access for patients? Host Dr. Lee Freedman welcomes Dr. Benjamin Jackson to answer these questions and the latest innovations in vascular surgery at the University of Pennsylvania Hospital. Dr. Jackson is an Assistant Professor of Surgery in Radiology at the University of Pennsylvania Hospital.

Oct 02 2014

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Rank #4: Beyond Dry Eyes: Signs of Sjogren's Syndrome

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Host: Lee Freedman, MD
Guest: Frederick Vivino, MD

Sjogren's syndrome is a commonly overlooked autoimmune disorder. Dry eyes and whole-body dryness are just two of the symptoms of Sjogren's syndrome that can suggest other conditions as well. How does Sjogren's present itself beyond dry eyes, and how severe is the condition? Dr. Frederick Vivino, clinical associate professor of medicine at the University of Pennsylvania School of Medicine, describes some of the tests and therapies available for Sjogren's syndrome to host Dr. Lee Freedman.

Produced in Cooperation with

Dec 08 2008

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Rank #5: Neck and Back Pain: When Should You Refer Your Patients to a Neurosurgeon?

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Host: Matt Birnholz, MD
Guest: Patrick J. Connolly, MD

Back and neck pain is extremely common, with 80-90% of people experiencing some pain within their lifetime. About 90% of cases resolve within six weeks, but for those patients whose pain persists, questions arise as to who should be referred next for further consultation. While patients often see a spine specialist at first, the care journey sometimes leads to a neurosurgeon or orthopaedic spine surgeon. Can this pathway from primary care to neurosurgery or orthopaedic surgery ever be expedited?

Dr. Patrick Connolly, neurosurgeon at Penn Medicine joins host Dr. Matt Birnholz to discuss when primary care physicians should consider referring patients to neurosurgeons for neck and back pain. Dr. Connolly will also discuss the different types of surgical options for patients seeking prolonged back and neck pain relief.

Feb 13 2017

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Rank #6: Surgical Advances in Knee Osteoarthritis

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Host: Lee Freedman, MD
Guest: Craig Israelite, MD

Dr. Craig Israelite, assistant professor of orthopedic surgery at the University of Pennsylvania School of Medicine, discusses a series of approaches to knee osteoarthritis. A brief review of non-surgical treatment is followed by a discussion of image-guided surgery, minimally invasive surgery, partial knee replacements and the post-operative use of multi-modal pain strategies. Dr. Lee Freedman hosts.

Jan 24 2008

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Rank #7: Investigational Approaches to Structural and Valvular Heart Disease

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Guest: Howard C. Herrmann, MD
Host: Lee Freedman, MD

We are increasingly able to turn to non-surgical therapies for structural and valvular heart disease. Host Dr. Lee Freedman discusses investigational, catheter-based treatment with Dr. Howard Herrmann, professor of medicine, and director of interventional cardiology and the Cardiac Catheterization Laboratories within the University of Pennsylvania Health System. What new devices are making these advances possible? What are the procedural risks?

Aug 05 2008

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Rank #8: Innovative Options for Patients with Multiple Myeloma

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Host: Lee Freedman, MD

Multiple myeloma (MM) is an incurable malignancy of plasma cells. Although there have been significant advances in the survival of this condition over the past 15 years, understanding the progression from its precursor state and developing interventions to prevent MM would be significant advances. In this segment, host Dr. Lee Freedman speaks with guest Dr. Brendan Weiss, Assistant Professor of Medicine at the Hospital of the University of Pennsylvania at the Abramson Cancer Center.

Feb 09 2015

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Rank #9: Overuse Tendon Injuries: New Approaches

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Guest: Louis Soslowsky, PhD
Host: Lee Freedman, MD
Dr. Louis Soslowsky, from the University of Pennsylvania Health System, outlines how newer understanding of the mechanism of injury in overuse syndromes is leading to new approaches in treatment. Dr. Soslowsky shares his expertise in biomedical engineering to help doctors fine tune their approach to rotator cuff tendinosis, epicondylitis and other common clinical problems caused by overused tendons.

Nov 19 2007

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Rank #10: 4 Latest Advances in Epilepsy Treatment at Penn

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Host: Jennifer Caudle, DO
Guest: Kathryn Davis, MD, MTR
Guest: Timothy Lucas, MD, PhD

According to the epilepsy foundation, epilepsy is the 4th most common neurological problem in the U.S. – only migraine, stroke and Alzheimer’s disease occur more frequently. The average incidence of epilepsy each year in the U. S is estimated at 150,000, or 48 for every 100,000 people.

Host Dr. Jennifer Caudle talks with Doctors Kathryn Davis and Timothy Lucas about advances in treatment for epilepsy at Penn Medicine. Dr. Davis is Assistant Professor of Neurology and Medical Director of the Epilepsy Monitoring Unit and Epilepsy Surgical Program. Dr. Timothy Lucas is Assistant Professor of Neurosurgery, Surgical Director at the Penn Epilepsy Center, and Director of the Penn Center for Laser Neurosurgery.

Jul 18 2016

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Rank #11: Innovations in Diagnosis and Treatment of Multiple Sclerosis

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Host: Jennifer Caudle, DO
Guest: Joseph Berger, MD, FACP, FAAN, FANA

Multiple sclerosis is a notoriously difficult disease to diagnose early on. With no singular confirmatory tests yet available, physicians often become reluctant to identify MS in their patients, leading to years of diagnostic and treatment uncertainty. But new innovations are helping doctors establish earlier diagnoses and start more targeted treatments for MS patients.

Dr. Jennifer Caudle welcomes Dr. Joseph Berger, Professor of Neurology at Penn Medicine, to explore some of these innovations advancing MS diagnosis and treatment.

Aug 01 2016

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Rank #12: Differentiating the Dementias

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Guest: John Trojanowski, MD, PhD
Host: Lee Freedman, MD

Dr. Trojanowski discusses how to differentiate the types of dementia and how making these distinctions can lead to different approaches in terms of management.

Oct 17 2007

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Rank #13: The Role of Technology in Precision Medicine

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Host: Frank Russomano

There are far too many diseases that do not have proven means of prevention or effective treatments. As such, health care providers must gain better insights into the biology of these diseases to make a difference for the millions of patients who suffer from them. Precision medicine is an emerging approach for treatment and prevention that accounts for individual variability in genes, environment, and lifestyle. Host Frank Russomano welcomes Brian Wells, Associate Vice President of Health Technology and Academic Computing at Penn Medicine, to discuss how Penn Medicine contributes to the precision medicine initiative, from technological developments to supportive infrastructures.

Jul 13 2015

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Rank #14: Unclog the Arteries: Treatment Options for Arterial Disease

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Host: Barnett Mennen, MD
Guest: Grace Wang, MD, FACS

Unclogging patient arteries is a key step to preventing stroke in patients with arterial disease. Whether it be preventing the operative stage, or surgery itself, advances in treatment at Penn Medicine are seeking to lessen the effects of arterial disease.

Host Dr. Barry Mennen welcomes Dr. Grace Wang, vascular surgeon and Director of the Vascular Laboratory at the Hospital of the University of Pennsylvania. Dr. Wang highlights the importance of early detection in arterial disease, as well as the symptoms and risk factors of the disease. She will also discuss the current and upcoming surgical intervention options at Penn Medicine.

Jun 07 2017

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Rank #15: Pancreatic Cancer: Associated Signs, Symptoms, Risk Factors and Treatment Approaches

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Host: Jennifer Caudle, DO
Guest: Major Kenneth Lee, IV, MD, PhD

Though a relatively rare disease, pancreatic cancer remains at the forefront of clinical discussion due to its highly aggressive nature. Dr. Major Kenneth Lee, Assistant Professor of Surgery at Penn Medicine, estimates that pancreatic cancer will become the number 2 cause of cancer death by the year 2020. This projected rise in mortality is largely due to the need for better advancement in treatment options.

Join host Dr. Jennifer Caudle and guest, Dr. Major Kenneth Lee, as they discuss major signs and symptoms associated with a pancreatic cancer diagnosis, risk factors, and treatment options.

May 23 2017

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Rank #16: FDA-Approved Gene Therapy Reverses Blindness in Children & Adults

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Host: Jennifer Caudle, DO
Guest: Jean Bennett, MD, PhD
Guest: Albert Maguire, MD

Power couple Drs. Jean Bennett and Albert Maguire discuss how their new therapy for the RPE65 gene, which causes retinal blindness, was recently approved by the FDA to become the first gene therapy treatment for a genetic disease in the United States and the first worldwide treatment for inherited blindness. Not only do they delve into the mechanics of the corrected gene injection, but they also explain what this milestone means for patient eligibility and how their marriage has played a role in the success of their research partnership.

Dr. Jean Bennett is the F.M. Kirby Professor of Ophthalmology at the Perelman School of Medicine at the University of Pennsylvania, and Dr. Albert Maguire is a Professor of Ophthalmology at the Hospital of the University of Pennsylvania and Attending Physician in the Division of Pediatric Ophthalmology at Children’s Hospital of Philadelphia.

Apr 23 2018

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Rank #17: Heated Intraperitoneal Chemotherapy (HIPEC) for Advanced Abdominal Cancers

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Host: Lee Freedman, MD

Heated/Hyperthermic Intraperitoneal Chemotherapy (HIPEC) is one of the most innovative treatments available today for complex abdominal cancers. What is it? Who is a candidate? And, what are the expected outcomes for our patients? Host Dr. Lee Freedman welcomes Dr. Giorgos Karakousis, Assistant Professor of Surgery at the Hospital of the University of Pennsylvania to discuss HIPEC.

Oct 02 2014

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Rank #18: Novel Treatments for Diabetes

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Guest: Mitchell Lazar, MD, PhD
Host: Lee Freedman, MD
Dr. Lazar discusses exciting new innovations in our approach to both type I and type II diabetes including Islet cell transplantation, medications for beta cell preservation and new insights into the control of obesity.

Oct 12 2007

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Rank #19: New Surgical Options for Spinal Disorders

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Guest: William Welch, MD
Host: Lee Freedman, MD

Advancing surgical treatments and devices are producing better outcomes for patients with spinal problems. How do these innovations alleviate pain associated with spinal stenosis, spinal metastases and spine trauma? Dr. William Welch, chief of neurosurgery at Pennsylvania Hospital, describes new spinal implants, including the X-STOP device, and motion preservation systems that are replacing traditional fusions.

Jan 25 2008

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Rank #20: The Diabetes Epidemic

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Guest: Mitchell Lazar, MD, PhD
Host: Lee Freedman, MD
The CDC has ominously projected that one in three children born in the year 2000 will develop diabetes in his or her lifetime. Mitchell Lazar, MD, PhD, professor of medicine and genetics at the University of Pennsylvania School of Medicine and director of the Penn Diabetes Center, discusses the magnitude of the diabetes epidemic. What can we do to prevent the CDC’s prediction from materializing?

Oct 12 2007

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