Cover image of Foundations of Computational and Systems Biology

Foundations of Computational and Systems Biology

Foundations of Computational and Systems Biology

Ranked #1

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Lecture 14: Predicting Protein Interactions

Lecture 14: Predicting Protein Interactions

This lecture is on predicting protein interactions. He discusses structural predictions of protein-protein interactions.... Read more

16 Jun 2015

1hr 11mins

Ranked #2

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Lecture 21: Synthetic Biology: From Parts to Modules to Therapeutic Systems

Lecture 21: Synthetic Biology: From Parts to Modules to Therapeutic Systems

This guest lecture by Prof. Ron Weiss is on synthetic biology. Prof. Weiss describes how he came to be a synthetic biolo... Read more

16 Jun 2015

1hr 21mins

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Ranked #3

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Lecture 20: Human Genetics, SNPs, and Genome Wide Associate Studies

Lecture 20: Human Genetics, SNPs, and Genome Wide Associate Studies

This lecture by Prof. David Gifford is on human genetics. He covers how scientists discover variation in the human genom... Read more

16 Jun 2015

1hr 17mins

Ranked #4

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Lecture 2: Local Alignment (BLAST) and Statistics

Lecture 2: Local Alignment (BLAST) and Statistics

In this lecture, Professor Burge reviews classical and next-generation sequencing. He then introduces local alignment (B... Read more

16 Jun 2015

1hr 16mins

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Ranked #5

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Lecture 9: Modeling and Discovery of Sequence Motifs

Lecture 9: Modeling and Discovery of Sequence Motifs

This lecture by Prof. Christopher Burge covers modeling and discovery of sequence motifs. He gives the example of the Gi... Read more

16 Jun 2015

1hr 22mins

Ranked #6

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Lecture 16: Protein Interaction Networks

Lecture 16: Protein Interaction Networks

This lecture by Prof. Ernest Fraenkel is on protein interaction networks. He covers network models, including their stru... Read more

16 Jun 2015

1hr 20mins

Ranked #7

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Lecture 13: Predicting Protein Structure

Lecture 13: Predicting Protein Structure

This lecture on predicting protein structure covers refining a partially correct structure. Methods include energy minim... Read more

16 Jun 2015

1hr 4mins

Ranked #8

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Lecture 3: Global Alignment of Protein Sequences (NW, SW, PAM, BLOSUM)

Lecture 3: Global Alignment of Protein Sequences (NW, SW, PAM, BLOSUM)

In this lecture, Prof. Burge discusses global sequence alignment and gapped local sequence alignment. He later talks abo... Read more

16 Jun 2015

1hr 20mins

Ranked #9

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Lecture 4: Comparative Genomic Analysis of Gene Regulation

Lecture 4: Comparative Genomic Analysis of Gene Regulation

Prof. Burge discusses comparative genomics. He begins with a review of global alignment of protein sequences, then talks... Read more

16 Jun 2015

1hr 22mins

Ranked #10

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Lecture 5: Library Complexity and Short Read Alignment (Mapping)

Lecture 5: Library Complexity and Short Read Alignment (Mapping)

Prof. Gifford talks about library complexity as it relates to genome sequencing. He explains how to create a full-text m... Read more

16 Jun 2015

1hr 20mins

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