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Science

Base Pairs

Updated 5 days ago

Science
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Cold Spring Harbor Laboratory's Base Pairs podcast ​tells​ stories that ​convey​ the power of genetic information – past and present.Named among the 2018 Webby Awards’ “five best podcasts in the world” for the subjects of science and education.Presented the Platinum Award for podcasting by PR News.

Read more

Cold Spring Harbor Laboratory's Base Pairs podcast ​tells​ stories that ​convey​ the power of genetic information – past and present.Named among the 2018 Webby Awards’ “five best podcasts in the world” for the subjects of science and education.Presented the Platinum Award for podcasting by PR News.

iTunes Ratings

33 Ratings
Average Ratings
24
3
3
1
2

Beautiful science

By stuman914 - Feb 06 2019
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Listening for 2nd time. Wonderful data well done!!!

Good but too infrequent

By drjonRohde - Jan 06 2019
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I have followed base pairs since first episode . More serious but posted irregularly. The initial series was logical and progressive but recently sporadic and not linked to a logical sequence . A better planned series is needed to reach 5 stars.

iTunes Ratings

33 Ratings
Average Ratings
24
3
3
1
2

Beautiful science

By stuman914 - Feb 06 2019
Read more
Listening for 2nd time. Wonderful data well done!!!

Good but too infrequent

By drjonRohde - Jan 06 2019
Read more
I have followed base pairs since first episode . More serious but posted irregularly. The initial series was logical and progressive but recently sporadic and not linked to a logical sequence . A better planned series is needed to reach 5 stars.
Cover image of Base Pairs

Base Pairs

Updated 5 days ago

Read more

Cold Spring Harbor Laboratory's Base Pairs podcast ​tells​ stories that ​convey​ the power of genetic information – past and present.Named among the 2018 Webby Awards’ “five best podcasts in the world” for the subjects of science and education.Presented the Platinum Award for podcasting by PR News.

Rank #1: 12 - Good Genes, Bad Science

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In the early 1900s, American science took a wrong turn toward eugenics. In this episode, we talk with experts in both science and history about what we can learn from this dark period in today’s age of unprecedented control over the genome.
Oct 13 2017
27 mins
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Rank #2: 8 – Dark Matter of the Genome (part 1)

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Could “genome” be a misnomer? The name implies that our genetic information is mainly genes, yet when the Human Genome Project was completed in 2003, it revealed that genes comprise a tiny minority. About 98 percent of the genome is something else — a kind of genomic dark matter.

We chat with an astrophysicist-turned-genome-biologist, Assistant Professor Molly Hammell, about how she ended up studying a type of genomic dark matter called transposons.
Mar 14 2017
23 mins
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Rank #3: 12.5 - Big Decisions

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Who will use CRISPR to alter their child's DNA? Who gets to decide which traits are desirable? Following up on our last episode, "Good Genes, Bad Science," we hear from David Micklos, executive director at CSHL’s DNA Learning Center, and Miriam Rich, CSHL Archives Sydney Brenner Research Scholar and doctoral student at Harvard, on these big questions.
Nov 15 2017
13 mins
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Rank #4: 3 - Non-modern Family

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From the scale of a single ancient murder victim to interactions between large groups of humans and Neanderthals who lived 100,000 years ago, genetic information holds many secrets about human history.

In this episode, "Ötzi the Iceman" and Dr Adam Siepel help us expose new secrets of the human genome.
Aug 15 2016
17 mins
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Rank #5: 10 – CRISPR vs Climate Change

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Much of the hype around the genome editing tool known as CRISPR focuses on its potential to cure genetic diseases. But our bodies need more than a healthy genome to survive and thrive—they also need food, and that’s where we may see CRISPR’s earliest effects on our lives. In this episode, we talk with plant scientist and Associate Professor Zach Lippman about the threats that climate change poses to agriculture, and how CRISPR could help overcome them.
Jun 14 2017
24 mins
Play

Rank #6: 14 - The Cancer Answer That Wasn't

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We look at the "reproducibility crisis" in science, and dive into a case in which cancer researchers discovered something completely unexpected while experimenting with a supposed drug target.
Mar 15 2018
29 mins
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Rank #7: 7 – The Brain Atlas

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One in six people suffers from a mental disorder, and yet, compared to cancer and infectious disease, neuropsychiatric treatment options have barely improved since the 1950s. But why is that? In this episode of Base Pairs, we explore some of the problems neuropsychiatric drug discovery faces… and how a single, simple method may help.
*Cover image by Vacon Sartirani
Dec 14 2016
26 mins
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Rank #8: 9 – Dark Matter of the Genome (part 2)

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One scientist’s junk is apparently everyone’s treasure! They just haven’t realized it yet. . . In this episode of Base Pairs, we question the mythos that is “junk DNA” and explore how and why scientists are becoming enthralled by the mysterious non-coding portions of the genome.
Apr 14 2017
25 mins
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Rank #9: 15 – The Immune System, Unleashed

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You may have heard of it; "immunotherapy" has started to appear in headlines over the last few years. In this episode, however, we reveal that the practice of cancer immunotherapy is actually far older than even our understanding of the immune system! We also talk to a CSHL researcher who is showing that the immune system doesn’t even need to be engineered to kill cancer. It just needs to be unleashed.
May 15 2018
25 mins
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Rank #10: 13 – A Lesson in Class

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No, we're not talking about high society or your biology class! In this episode, we share three distinct stories about classification in the life sciences and how genetic information is changing how we define important categories.
Dec 15 2017
21 mins
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