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Science Vs: Artificial Sweeteners - not so sweet?. Low calorie, no calorie and so sweet. Artificial sweeteners just seem too good to be true. Is there a catch? We dig into two big questions: Do artificial sweeteners cause cancer, and are they making us fat? We talk to Prof. John Glendinning, Prof. Susie Swithers, Dr. Kieron Rooney, and PhD student Jotham Suez about the latest research. Plus we do a fun experiment with PJ Vogt and Alex Goldman from Reply All! Also, please sign up for our brand spanking new newsletter! We’ll share science that’s been blowing our minds, plus great content like the most amazing calculation from an academic of how much bigger 323 African Elephants are than nuclear waste. Head to: https://gimletmedia.com/newsletter/ Our Sponsors:Postmates - New customers get a $100 credit by downloading the app and entering the promo code SCIENCEWordpress - go to wordpress.com/science to get 15% off a new websiteHello Fresh - For $30 off your first week of meals go to hellofresh.com and enter the promo code SCIENCEVS30 Credits: This episode has been produced by Ben Kuebrich, Heather Rogers, Shruti Ravindran and Wendy Zukerman.Kaitlyn Sawrey is our senior producer. We’re edited by Annie-Rose Strasser. Production assistance by Stevie Lane. Fact checking by Michelle Harris. Original music and mixing by Bobby Lord. Extra thanks to Dr. Mary Pat Gallagher, Peter Bresnan, Euromonitor International and ubiome. Selected References:Prof. Susie Swithers’s study on artificial sweeteners and feeding behavior in ratsA 2015 systematic review of the relationship between artificial sweetener consumption and cancer in humansJotham Suez’s study on artificial sweeteners and the gut microbiome
Stuff You Should Know: SYSK Selects: How Willpower Works. You use it every day to overcome your lower self (which wants you to eat cake until your vision blurs) in pursuit of the goals of your higher self (which wants you to not develop Type-II diabetes). Yet it was only in the 1990s that researchers began to understand what makes our willpower and how it behaves.
Masters of Scale with Reid Hoffman: The Reid Hoffman Story (Part 1) — Make everyone a hero. In this special episode, we turn the tables on host Reid Hoffman. He’s the guest and we tell his story, while proving a theory that’s perfect for Reid: You can chart an epic journey to scale, if you make everyone a hero along the way. Guest Host is June Cohen, Executive Producer of Masters of Scale, CEO of WaitWhat, and former Executive Producer of TED. Cameo Apperance: Matthew Mercer, host of the web series Critical Role.
Y Combinator: #107 - Vinod Khosla and Sam Altman. Vinod Khosla is the founder of Khosla Ventures, a firm focused on assisting entrepreneurs to build impactful new energy and technology companies. Previously he was the founding CEO of Sun Microsystems, where he pioneered open systems and commercial RISC processors.How to Build the Future is hosted by Sam Altman.***Topics00:30 - Vinod’s intro01:20 - A zero-million-dollar company vs a zero-billion-dollar company4:20 - What percentage of investors in Silicon Valley are good long-term company builders?4:50 - Who has earned the right to advise an entrepreneur?6:50 - Which risk to take when7:20 - Helpful board members8:15 - Who to trust for what advice11:00 - First principles thinking and rate of change13:00 - Evaluating a candidate in an interview14:15 - How much should a founder have planned and how ambitious should a founder be?16:30 - Recruiting great people19:00 - Building a phenomenal early team20:20 - Being generous with early employee equity27:00 - Gene pool engineering27:18 - The art, science, and labor of recruiting28:20 - How founders should think about investors31:00 - Doers vs pontificators32:00 - What does Vinod want to do in the next ten years?32:10 - Reinventing Societal Infrastructure with Technology