Rank #1: Keto Battles Cancer – Miriam Kalamian, EdM, MS, CNS, Author of Keto for Cancer: Ketogenic Metabolic Therapy as a Targeted Nutritional Strategy – New Discoveries—The Power of Nutrition, Fighting Disease
Miriam Kalamian, EdM, MS, CNS, discusses her work as an educator and nutrition expert, and talks extensively about the connection between diet and disease.
Kalamian has devoted much of her life to the study of nutrition. She is board certified in nutrition (CNS), bestowed upon her by the Board for Certification of Nutrition Specialists. As a noted nutrition consultant and educator, she spends a great deal of her time focused on the importance of diet in an overall healthy lifestyle. And as a successful author and nutrition expert she is interested in the implementation of ketogenic therapies, and has written extensively on the topic. Kalamian holds a master of education (EdM) from Smith College and a master of human nutrition (MS) from Eastern Michigan University.
Kalamian discusses her background and what led to her current career focus. As she recounts, her world was rocked back in 2004 when her young son was diagnosed with a brain tumor. Standard therapies did not stop the aggressive progression of his disease, and thus it was clear to Kalamian that she simply had to go in a different direction to fight for her son. After much reading and research, Kalamian discovered Dr. Thomas Seyfried’s extensive research that was based on the ketogenic diet as a means to fight cancer. She discusses in detail, the journey she went through with her son, and talks about the ways in which the body turns up its power to fight, when a stricter diet commands the body to work efficiently.
The nutrition expert delves into the inner-workings of the body and its abilities to handle and process foods. She talks about the effects of too much protein in a diet, and explains what happens internally. She explains how cancer cells work and how exercise and diet combine to provide benefits. Kalamian explains fatty acids and ketosis, and the removal of glucose from the bloodstream. As she states, low-impact exercise, such as a nice walk, helps to remove glucose from the bloodstream in a safe and effective way. She explains that nutrition, when controlled, can benefit the body’s health while simultaneously working against cancer.
The effects of a ketogenic diet can have a significant impact on some cancer patients in combination with their doctor’s other treatments and therapies. While keto may not be the sole solution, it certainly can enhance traditional medicine treatments.
Rank #2: Help, I Can’t Sleep! – Michael A. Tompkins, PhD, ABPP, Co-Director of the San Francisco Bay Area Center for Cognitive Therapy – The Importance of Sleep – Why We Need It and What To Do When We Aren’t Getting Enough Quality Sleep
Michael A. Tompkins, PhD, ABPP, co-director of the San Francisco Bay Area Center for Cognitive Therapy (sfbacct.com), delivers an informative overview of mental health issues and contributing factors that play a significant role in how we sleep and the quality of our sleep.
Dr. Tompkins is an experienced licensed psychologist, board certified in behavioral and cognitive psychology. He is an accomplished author and outspoken advocate for mental health. Dr. Tompkins has held, and currently holds, significant leadership roles with various, important mental health centers and educational institutions. He is co-director of the San Francisco Bay Area Center for Cognitive Therapy, assistant clinical professor at the University of California, Berkeley, as well as Diplomate and Founding Fellow of the Academy of Cognitive Therapy. Additionally, Dr. Tompkins works as a trainer and consultant for the Beck Institute for Cognitive Behavior.
Dr. Tompkins discusses his nearly 30-year career in mental health, treating primarily anxiety and mood disorders. He states that most people with these kinds of disorders do experience difficulty with sleep. He details CBTI (cognitive behavioral therapy for insomnia) and his work with teens who have anxiety and sleep disorders. Insomnia is defined as a difficulty going to sleep or staying asleep, which limits the amount of restorative sleep that we all need. He explains how sleep disrupters, such as stress or travel, impact the sleep cycle. Further, he states that those who struggle to get quality sleep often worry about it, which increases anxiety and exacerbates the problem, or they try to adjust their sleep schedule, which often does not work because regularity of a sleep schedule is critical for the body to get into a working pattern such that restorative sleep can flourish.
Dr. Tompkins’ book, The Insomnia Workbook for Teens, lays out a step-by-step process for achieving better sleep, proven-effective strategies to help the sleep deprived get to sleep and stay asleep. The book explains the many and varied reasons we experience insomnia, and offers advice on how to target and deal with sleep disrupters such as caffeine and sugar. Teens especially need quality sleep as their lifestyles today are fast and furious, and it is difficult to rise to the challenges of each day when we’re sleep deprived and left feeling exhausted, grouchy, and unprepared for daily tasks. Dr. Tompkins coauthored the book with his esteemed colleague, Dr. Monique Thompson, also a licensed clinical psychologist. Dr. Thompson holds a master’s degree from the University of Pennsylvania and a doctoral degree in clinical psychology from California School of Professional Psychology. She is a certified cognitive therapist and also a Diplomate of the Academy of Cognitive Therapy. She treats a myriad of mental health issues such as depression, various anxiety disorders (social anxiety, phobias, and panic), and sleep disorders, as well as attention problems, life transitions, and more.
Dr. Tompkins provides an overview of one of their primary goals: focusing on sleep efficiency, which is entirely different than simply looking at quality or quantity of sleep. He discusses various stimulus control strategies and other methods that people can utilize to help get them back on track with their sleep. He states that nearly 80% of the individuals they help with primary insomnia can often benefit from sleep restriction, essentially getting them to stop trying to catch up on sleep, but to focus on having consistent go to bed, and get out of bed times. Additionally he discusses other effective techniques such as breathing exercises, mindful meditation, muscle relaxation, and more. Dr. Tompkins talks about wind down routines and relaxation in general, and the importance of getting one’s body and mind to a state in which all systems are ready to fall asleep willingly.
The sleep specialist and mental health educator discusses the particular issues that teens face, as they are literally going through an organic change in brain development that causes them to want to begin sleep later in the evening and then sleep in later come morning. And with elevated stress in teens’ lives, and the use of social media, all can keep teen minds activated, which leads to sleep disturbances or a general difficulty with falling asleep or staying asleep. He details the types of skills that they teach in CBTI to help teens with their various sleep issues.
Dr. Tompkins discusses melatonin and other supplements, but he stresses that chronic insomnia sufferers may not benefit from melatonin, etc. Ultimately, insomnia sufferers must find a way to focus on wind down time and a consistent schedule of sleep. Additionally he talks about genetic inheritances that may contribute to sleep problems, such as chronotype (when we feel like sleeping naturally) and mental arousability, which many insomniacs tend to be prone to.
Dr. Tompkins is the author of multiple scholarly articles, chapters on cognitive behavior therapy, and books covering related subjects. He treats adults, adolescents, and children with anxiety disorders, as well as obsessive compulsive disorder, health anxiety, stress, insomnia, repetitive behaviors, elimination disorders, Tourette’s and tic disorders.
Rank #3: Plants as the Masters of Chemistry—Frantisek Baluska, Ph.D.—Institute of Cellular and Molecular Botany, University of Bonn
Rank #4: King Ketone – Dominic D’Agostino, PhD, Associate Professor, University of South Florida – The Impressive Power of Ketones and How Our Diets Hold the Key to Improved Cognition, Increased Energy, Weight Control, and Disease Treatment
Dominic D’Agostino, PhD, is an associate professor at the University of South Florida’s Morsani College of Medicine, as well as the Department of Molecular Pharmacology and Physiology. D’Agostino’s focus of teaching is quite diverse as he educates in the areas of physiology, neuropharmacology, biochemistry (medical), cell metabolism, and signaling. D’Agostino’s laboratory tests metabolic-based strategies for battling multiple human health problems such as seizures, epilepsy, neurodegenerative diseases, and more.
The associate professor leads a discussion on various metabolic therapies including ketogenic diets, and the benefits of ketone supplements. Remarkably, one’s level of ketosis can be assessed and measured in blood and urine samples. Ketosis is a metabolic state; essentially, when an individual removes carbohydrates from their diet they in turn force their body to deplete its stores of glycogen and seek out a new fuel source. As this takes place, ketosis is initiated when the body begins converting fat into ketones as its new, powerful fuel. While the shift may be a major adjustment for the body, and for individuals attempting to make the push toward a ketogenic diet, the results are obvious for most, with many people reporting a general feeling of well-being with more energy also. As D’Agostino explains, those who suffer from age-related cognitive decline, inflammation, or weight problems, all stand to benefit greatly from the shift to a ketogenic diet and the stimulation of ketosis.
The physiology and cell metabolism professor explains how exogenous ketone supplementation can enhance the metabolic efficiency of the body, which can increase cognition and workflow activity. While many seek to get fully into a state of ketosis, this may not be the ultimate goal, for the goal is simply to feel better, and approximating the state may offer some benefits. Many are aware that ketosis can help with weight loss and appetite control, but as health seekers come for the weight loss they will more than likely also benefit from an advanced mental focus, more energy, and increased levels of HDL cholesterol. Additionally, ketosis can help to lower blood pressure and aid in the fight against type II diabetes. D’Agostino digs deep into the scientific workings behind variations on ketone supplementation. He discusses MCTs, or medium-chain triglycerides, and ketone salt combinations that can be delivered before low carbohydrate meals that can buffer the rise in glucose. The professor explains how the ketone benefit works within the body for suppression of appetite and increased cognitive function, and further, he relates how individuals can see improvements across the line with exogenous ketones even without adhering to an absolute ketogenic diet. D’Agostino provides some insight into ketone salts and ketone esters and their affect on the osmotic load in the gut. Ultimately, as D’Agostino explains, the scientific study of ketones is proving that many health issues can be improved by controlling the diet.
Rank #5: The Ketogenic Defender – Dominic D’Agostino, PhD, Associate Professor, University of South Florida, Department of Molecular Pharmacology and Physiology – The Potential Benefits of a Ketogenic Diet in Disease Treatment
Dominic D’Agostino, Ph.D., delivers an informative overview of the potential positive impact of ketogenic diets for disease prevention and treatment. He discusses how many cancers such as endometrial cancer and pancreatic cancer are associated with hyperglycemia, which is a hallmark of type II diabetes.D’Agostino is a tenured professor at the University of South Florida. Working with students at the Morsani College of Medicine and the Department of Molecular Pharmacology and Physiology, D’Agostino’s primary focus is in the areas of neuroscience and neuropharmacology, medical biochemistry, and physiology.
As a research scientist at the Institute for Human and Machine Cognition, D’Agostino aggressively pursues his research in methods to optimize and maximize the health, safety, and resilience of soldiers in combat, as well as astronauts. As a laboratory scientist D’Agostino and his team develop and test various metabolic-based strategies for seizures, epilepsy, cancer, and select neurodegenerative diseases. His primary focus for over a decade has been centered upon the many potential anticonvulsant and neuroprotective mechanisms of a ketogenic diet as well as ketone metabolite supplementation.
D’Agostino is an active member of the Undersea and Hyperbaric Medicine Society, Society of Neuroscience, Aerospace Medical Association, American Physiological Society, and the American Association of Cancer Research. He holds a Ph.D. and BS from the esteemed Robert Wood Johnson Medical School and Rutgers University, respectively.
D’Agostino discusses his current and primary focus on brain cancer and how the ketogenic diet has historically been used to treat epilepsy, thus brain tumor patients experiencing seizures may see significant benefit from a dietary change to this low-carb, high-fat, protein-adequate diet. He talks about the Warburg effect, the phenomenon in which cancer cells produce extra energy via increased oxygen-dependent glycolysis that is then followed by lactic acid fermentation with a secretion of lactate. D’Agostino provides information on cell metabolism; the ATP molecule, which is the nucleotide specifically known in biochemistry as the ‘molecular currency’ of cell to cell energy transfer; as well as mitochondria and the links between diet and some cancers.
The nutrition and health Ph.D. outlines other important and relevant studies, such as the work of Valter Longo, the Italian-American biogerontologist and cell biologist who is known primarily for his study of the role fasting and nutrient response genes play in disease and cellular protection. Additionally, he discusses the protective effects of short-term dietary restrictions as well as fasting, and the potential importance of ketones for metabolic health.
While weight loss is essentially a good side effect of a ketogenic diet, the metabolic benefits provide even more advantages, in addition to the healthy effect of losing weight. He discusses the beneficial impact of decreasing glucose availability to tumors and implementing dietary restrictions as part of a treatment plan for some cancers. The shift in brain metabolism from glucose to ketones can actually reduce neuronal hyperexcitability and oxidative stress, which can enhance brain energy metabolism. D’Agostino feels this methodology can be used to treat a vast array of pathologies, including cancer.
Additionally, D’Agostino presents an important analysis of the microbiome, which is the community of microorganisms such as fungi, bacteria, and viruses that inhabit a specific environment, especially in regard to microorganisms living within or on the human body. He provides his opinion on the variations in microbiomes and how the optimal microbiome can differ based upon food eaten, geographical location, and other factors, and how a ketogenic diet and periodic fasting can help purge the overgrowth of the microbiome, and help return the body to balance. And D’Agostino discusses the glucose-ketone index, and how individuals seeking a healthier dietary balance and increased energy can monitor their index to ensure they are reaching ketosis with regularity for maximum health benefits.
Rank #6: The Myth of Aging – Aubrey de Grey, PhD, Chief Science Officer and Co-founder of SENS Research Foundation – Debunking the Myth That Nothing Can Be Done About Aging, Through Scientific Research and Development
Aubrey de Grey, Ph.D., Chief Science Officer and Co-founder of SENS Research Foundation, delivers an overview of aging and the many health problems that develop in our advanced years.
Dr. de Grey is a respected member of the science community; he is the noted biomedical gerontologist who devised the innovative SENS platform and co-founded the SENS Research Foundation to further it. Dr. de Grey has written about his work and as an established researcher, he has been appointed to the editorial and scientific advisory boards of many journals, organizations, etc. Dr. de Grey is a Fellow of the Gerontological Society of America as well as the American Aging Association. He holds a BA in Computer Science and a Ph.D. in Biology from the prestigious University of Cambridge.
Dr. de Grey discusses his research in aging and the motivations for tackling the career. As he states, aging is the number one medical problem as it causes more suffering. He was motivated to research in this area because he found that not enough was being done to focus on aging and the myriad of problems that come with it. He talks about the many excuses that are given as reasons to simply accept aging as it is, or not focus on it at all, such as “it’s inevitable…everything ages,” or the philosophical—“death gives meaning to life,” or social—“maybe we could do this, but it would create new problems worse than the problem we are solving.” And as the Ph.D. states, none of these excuses stand up to even the faintest scrutiny, however, they still remain quite popular.
Dr. de Grey explains that ‘why’ and ‘how’ we age are fairly well understood, but it is the understanding of what we already know that is important, to take the information we know to be true and utilize that to design and implement therapies that will prevent the health problems of old age. And this is the core of what Dr. de Grey’s foundation, SENS Research, seeks to accomplish. SENS Research Foundation works to create, promote, and provide wide-ranging access to all kinds of therapies that can cure and prevent the diseases and detrimental disabilities of aging by essentially repairing the damage that builds up within our bodies over long periods of time. SENS Research seeks to change the way the world researches and thus cares for age-related ill health.
The Ph.D. discusses stem cell therapy and its ability to repair the damage, loss of cells, etc. As he explains, stem cells can be injected that target areas within the body and repair damage, replace lost cells, and thus keep the body area, organ, etc. functioning in a healthier state. He explains in detail how cells function and the processes used to make genetic modifications. Additionally, Dr. de Grey expounds upon the kinds of complex research they engage in at his foundation, and the types of conditions that they seek to bring more understanding to in order to combat them.
Rank #7: Virtual Reality Stadiums Featuring Your Favorite Sports Teams, No Matter Where You Are—Symon Perriman—FanWide
There’s nothing quite like the energy and excitement of seeing your favorite sports team in person while surrounded by hundreds or thousands of other fans rooting right along with you, but for the 100 million Americans who don’t live in the same town as their favorite team, this experience is difficult if not impossible to come by. As the president and founder of FanWide, Symon Perriman set out to change this.
FanWide is the world’s largest fan club network that’s connecting likeminded sports fans—regardless of where they live or travel—in a way that until now has only been possible for those who live in the local market. How are they doing it? By creating a virtual stadium at every sports bar around the country where fans can interact, play games, and cheer on their team in unity. But that’s not all: FanWide incentivizes fans for showing up to events by providing rewards such as free beer, contest entries, and the potential to win cryptocurrency tokens that can be spent on game tickets, sports merchandise, and sports apparel.
“I found that sports were one of the few things that really transcend where you’re from, what language you speak, your gender, your ethnicity…if you can find fans from the same team, it builds up that immediate bond or connection, and we’re providing…an easy way to have that bond and find those people from the same tribe or background through our digital platform, and then bring them together in real-world events,” says Perriman.
Tune in for all the details and visit fanwide.com for an event near you.
Rank #8: Scandals & Frauds – Rebecca Jarvis, Chief Business, Technology & Economics Correspondent for ABC News – Analyzing the Newsmakers - Making Sense of Some of the Most Alarming Business Scandals and Frauds of Our Time
Rebecca Jarvis, Chief Business, Technology & Economics Correspondent for ABC News provides interesting details on her long career in journalism and specifically the amazing story of disgraced entrepreneur, Elizabeth Holmes and her company, Theranos.
Jarvis is a seasoned journalist. In addition to her prominent work with ABC News, she serves as host and managing editor of the popular podcast No Limits with Rebecca Jarvis, as well as host and managing editor of Real Biz with Rebecca Jarvis. Her extensive work for ABC News includes critically acclaimed shows such as World News Tonight with David Muir, Nightline, 20/20, This Week with George Stephanopoulos, and Good Morning America. Throughout her impressive career she has regularly interviewed innovators and visionaries such as Warren Buffett; Sheryl Sandberg; Richard Branson; Diane von Furstenberg; and GM’s first woman CEO, Mary Barra, just to name a few. From presidential elections to the Great Recession, the Madoff scandal and the crash of Bear Stearns and Lehman Brothers, if it’s important business news, Jarvis has covered it.
Jarvis discusses the riveting story of Elizabeth Holmes and Theranos. Jarvis’ work on The Dropout, a documentary podcast by ABC Radio & ABC News Nightline that covers the story of the aforementioned Holmes, has received critical praise. The Dropout explores the ambition and fame that went awry for the world’s youngest self-made woman billionaire. It seeks to unravel the story of Holmes and get to the bottom of how a woman at the top of her game, who was often referred to as ‘the next Steve Jobs,’ could lose everything and face severe criminal charges. Theranos was a health technology corporation that experienced a meteoric rise in the medical technology industry with what was then heralded as breakthrough technology—a means to perform blood tests with extremely smaller amounts of blood than had been historically possible. However, if it sounds too good to be true it often is, as Holmes was later exposed for making false claims about the company and the tech, and was indicted on wire fraud and conspiracy charges. Jarvis explains how she became intrigued by not only the technology Theranos was proposing but also the scores of big-dollar investors who jumped on board early stage to back the so-called groundbreaking technology. Jarvis comments at length about how amazing it is that time after time so many truly smart people can be fooled by swindlers like Bernie Madoff, Elizabeth Holmes, and others like them. She describes it as “affinity fraud” in that people tend to trust those whom their friends and associates have already placed trust in. Jarvis goes on to say that Holmes was truly a brilliant woman to accomplish all that she did in high school, college, and beyond and that everyone who knew her was aware of her incredible aptitude in many areas. Unfortunately, she took a very wrong turn.
Further, Jarvis talks in general about business and investments. She explains that sometimes it is necessary to fight one’s own nature, and she cites examples of how some people have lost greater by quickly pulling their money out of the market when there is a slight shift. The lesson, she states, in terms of business and investment, is to always ask questions and get answers, and those who do often get it right.
Rank #9: Dropping Weight – Dr. Tro Kalayjian, Board-Certified Internal Medicine Physician and Weight Loss Expert – A Diet and Exercise Program That Produces Real Weight Loss, Reverses Medical Problems, and Improves Overall Heath
Dr. Tro Kalayjian is a board-certified internal medicine physician and weight loss expert who has passionately devoted his life to bringing good health and wellness to everyone. Dr. Kalayjian delivers an interesting and useful overview of his methods to achieve weight loss and health improvement.
Dr. Kalayjian has a medical degree from Touro Medical College and he completed his internal medicine residency in the Yale New Haven Health System at Greenwich Hospital where he served as a chief medical resident. A prolific publisher, Dr. Kalayjian has released a wide variety of important case reports and findings in the areas of binge eating disorder, food addiction, and achalasia— a rare disorder that makes it very difficult for foods and liquids to pass into the stomach. His therapeutic focus includes obesity, hypertension, diabetes, hyperlipidemia, and metabolic syndrome. Dr. Kalayjian recommends a combination of intensive lifestyle changes including diet, exercise, stress management, and mental health care to many of his patients seeking improved health.
Dr. Kalayjian discusses the emotional and metabolic issues that could make weight loss more challenging for some. He recounts stories of patients who have run into difficulty losing weight even after undergoing dramatic procedures such as gastric bypass surgery, etc. As Kalayjian explains, there are many reasons why weight loss can be difficult and he works with patients that have diverse issues that present challenges for them.
Kalayjian provides a basic overview of his four-month program, starting with comprehensive lab work, an initial ninety-minute session and weekly follow-ups for up to eight weeks. Additionally, lab work is redone to assess changes, and subsequent consultations follow. Kalayjian monitors weight, body fat, blood pressure, body/fat/water mass, heart rate, glucose and more, to get a complete picture of a patient’s body and how it is functioning. He states his average weight loss for the program is about 35 pounds, with extremes of as little as four pounds lost, and 120 pounds as the maximum lost. Kalayjian discusses how his process first begins with figuring out what is causing the obesity in a patient, and only after reaching his conclusion can he then get them started on an appropriate diet, such as low fat, or low carb, ketogenic, etc., that will yield the results they are seeking. And while his patients are working toward their goal, Kalayjian also offers opportunities for them to socialize in various ways with others who are also seeking weight loss, to create a sense of community, one that provides support. He details the process as patients move into months three and four that may involve some fasting, dietary restrictions, time-restricted feeding, and exercise. Additionally, he talks about the problems people have when they plateau and some options, such as intermittent fasting and hunger assessments that may help them get past it and begin losing weight again.
The diet and nutrition expert details the important role that metabolism plays in weight loss. And he explains how some of the TV show weight loss programs that push fast weight loss have permanently damaged participants’ metabolism by approaching weight loss the wrong way. As he states, weight loss is a process and he advises one pound per week for most patients, to ensure a safe, effective, long-term strategy that can provide lasting results.
Kalayjian explains that the vast array of ‘eat more, move less,’ ‘count calorie,’ and other conventional programs and ideas really do not work for most people. Kalayjian’s goal is to provide a better way for his patients to find success in their weight loss plan, to lose the weight and keep it off for life. He recounts how his wife offered encouragement that nudged him to embark on his own personal weight loss journey, an experience that has helped him to better understand how to help others. He takes his patients’ journeys very personally and feels that if they fail, he has failed, so he makes it a point of never letting them fail, even if they have specific metabolic difficulties that may make their path to success a bit of a longer one. Kalayjian explains that diet and nutrition have been proven to not only impact weight loss, but also many other diseases and pre-disease conditions, and he is incredibly passionate about helping patients improve their health and be well.
Rank #10: The Ketogenic Epilepsy Connection – Jade Nelson, Epilepsy Advocate, Health Educator, and Author of My Keto Toolkit – Better Health, Abundant Energy, and Feeling Well with a Ketogenic Diet and Lifestyle
Jade Nelson, speaker, coach, epilepsy advocate, community health educator, and author of My Keto Toolkit, delivers a passionate account of her journey to better health through lifestyle changes and the ketogenic diet. Nelson shares her story and details on her remarkable path to healing at her website (jadenelson.net). Nelson’s book, My Keto Toolkit, is equal parts a survival guide and overview of her path to becoming a ketogenic epilepsy warrior. Nelson shares her 31-year journey with an epilepsy diagnosis, her personal experience with self-care, the ketogenic diet, health insurance and more. The informative book provides tips, resources, and information on favorite products, as well as many personal recipes, etc., that can help people to take the first step toward a healthier life with more energy and a feeling of well being. It is a guide to a lifestyle that will truly be life-changing.
Nelson describes how a strict ketogenic diet worked for her, but that other might achieve positive results from variations on the diet, such as a modified Atkins, or simply a low-carb approach. Nelson describes the incredible changes she felt once she took the plunge into a ketogenic lifestyle, such as feeling more alert, having an abundance of energy, feeling happier, and living with a general sense of wellness within the body. Overall she was simply less emotionally drained, and she no longer needed those daily naps; her life was restored.
The nutrition authority offers valuable information on the importance of tweaking one’s diet to ensure it is providing the maximum health benefits. She discusses the process of gluconeogenesis, which is what happens when the body receives more protein than it needs and converts it into glucose, which can push someone out of ketosis. Nelson explains that the process of discovery and experimentation can lead ketogenic dieters to a plan that is optimum for them, as everyone is different internally to some degree. She stresses that the ketogenic diet will cause many to feel satiated more often, not as hungry as they might have been before beginning the diet, and the importance of monitoring the diet, especially if one’s body fat is low to ensure that body muscle is not adversely impacted.
Nelson outlines some helpful tips for those who are on the go. She states that there are more ketogenic products available in the marketplace today, including many travel items, oils, and supplementary foods that are grab-and-go and convenient. She explains that there are many ways to supplement meals when eating out or traveling, options that can round out the ketogenic diet and allow everyone to keep on track with their ketogenic routine and stay in ketosis. Additionally, she describes some of the ketogenic products that she has had success with but stresses that it is real food, not products, that is the key to success in a ketogenic lifestyle and diet.
The ketogenic educator discusses ketogenic specifics for women and some of the important issues to consider to ensure that their diet doesn’t adversely affect their natural cycle. She warns that excessively low caloric intake and insufficient nutrients can possibly cause some women to become amenorrheic, which is the loss of their period, so women should be aware, and adjust their diets accordingly to avoid this problem.
Nelson discusses her path to success on the ketogenic diet, and the many people she has worked with on an individual basis, as well as her coaching and live event speaking engagements where she outlines a wealth of information on the diet and nutrition in general. She encourages people to reach out to her through her website as well as through instagram (@thetraininsideme) and on facebook.
Rank #11: Sleeping Well? – Dr. Katharina Lederle, Human Sleep and Fatigue Specialist, Somnia – How Everyone Can Learn to Sleep Better
In this podcast, Dr. Katharina Lederle, a noted sleep and fatigue specialist at Somnia, provides a detailed overview of the importance of a good night’s sleep.
Dr. Lederle’s company, Somnia, seeks to educate the public and offer skills that can help people improve their sleep quality. Achieving better sleep can result in a significantly happier, healthier life. Somnia’s program works to resolve sleep problems and improve overall sleep habits. Dr. Lederle and her team of sleep specialists provide individualized services, including one-on-one private consultations designed to analyze an individual’s sleep problems and generate solutions.
Dr. Lederle grew up in a rural area near an army base, and the sounds of helicopters offered her a comfortable auditory background for optimum sleeping. But her dad had a totally different reaction, and this intrigued her, which may have ultimately led to her career in the study and improvement of sleep.
Dr. Lederle goes into detail about sleep cycles and she explains chronotypes, which are the behavioral presentation of one’s internal circadian rhythms. A particular chronotype is one’s desire to sleep and sleep better, at a particular time during a 24-hour cycle. As Dr. Lederle explains, everyone needs to discover their own chronotype and avoid input from society on this matter, because everyone has their own ideal chronotype that works best for them.
Dr. Lederle discusses sensitivity to light, and how light affects our internal body clocks. As she states, we are designed to sleep through the night and work in daylight hours, because our abilities in regard to night vision are quite poor by comparison.
Dr. Lederle uses her wide base of sleep knowledge and a hands-on approach, combined with her years of practical experience in sleep science and sleep therapy to help people feel better and get the quality sleep they need.
Rank #12: Ingestible Electronics: Developing a Novel Approach to Biomedical Device Manufacturing—Dr. Yong Lin Kong—University of Utah College of Engineering
As a professor in the mechanical engineering department at the University of Utah, Dr. Yong Lin Kong is focused on developing novel additive manufacturing technologies to create unique interwoven architecture and devices that can’t be created using conventional fabrication methods. By using a multi-scale, multi-material 3D-printing approach, Dr. Kong explains that the geometrical, mechanical and material difficulties present in conventional methods can be overcome, allowing for the creation of a broad range of 3D biomedical devices that can address a range of clinical needs. For example, one use case of this technology is ingestible electronics, which will not only allow for surgical integration of electronics in the human body to be bypassed, but also circumvent the inherent immune system response that would identify and attack such systems as foreign to the body.
The 3D-printing approach is also superior to conventional manufacturing processes in that it allows for the personalization of biomedical devices, tailored gastric residence time periods, and controlled dosage and release of drug compounds in the body. Dr. Kong makes for an insightful and compelling discussion, explaining the details of all this and more, including important safety measures for this technology, such as on-demand device disintegration in the event that an individual has a negative reaction to a device, how this approach could allow for the integration of electronic functionality into various prosthetics and regeneration implants, and what’s next on their itinerary.
Tune in for all the details and reach out with questions or requests for collaboration via firstname.lastname@example.org.
Rank #13: Identifying and Changing the Thoughts, Feelings, and Behaviors that Contribute to Insomnia—Alisha L. Brosse—Author of End the Insomnia Struggle
When you think of possible treatments for insomnia, the first thing that comes to your mind probably isn’t cognitive behavioral therapy (CBT), but Alisha Brosse, author of End the Insomnia Struggle, joins the podcast today to discuss why it should be. Simply put, CBT involves the interrelationship between the way we think about things, how we feel about those things, and how we respond behaviorally. And when CBT is applied to sleep disorders, it also involves the physiological contributions and consequences of our thoughts, feelings, and actions.
“We help people change their behaviors and attitudes so they can let their body do what it instinctively needs to do,” explains Brosse. Many people who suffer from insomnia begin to think night after night about the consequences of inadequate sleep, and how it will affect the following day. They’ll also change their behaviors, perhaps by staying in bed for longer (without actually sleeping), consuming more caffeine during the day, or cutting back on social activities at night. In CBT, these behaviors are referred to as compensatory, and are actually counterproductive to sleep.
Brosse offers an eye-opening discussion that touches on a variety of topics, including the methods and strategies used to help people who suffer from different types and stages of insomnia, a number of other conditions and factors that can either trigger a lack of sleep or be the consequence of it, and the common mistake of assuming that mental disorders always precede or are the cause of sleep issues. Tune in for all the details, check out her book on Amazon or Barnes and Noble, and visit her website at bouldercbt.com.
Rank #14: Total Health – Ben Bocchicchio, Doctor, Author, Health and Fitness Expert – High Intensity Exercise and Proper Diet For Maximizing Metabolism
Dr. Vincent “Ben” Bocchicchio, doctor, author, and health-oriented fitness expert delivers an interesting and important analysis of the body, exercise, and diet connection, and how we can all make positive changes that will improve our health significantly. Bocchicchio has over 40 years of experience in the fitness and health industry. He is a sought-after expert whose practical methods for achieving optimal health combine science with effective body conditioning and technology for top results in weight loss, and fitness. Dr. Bocchicchio was the pioneer developer of slow resistance training, a fitness technique that literally revolutionized the way people exercise.
Bocchicchio’s book, Fifteen Minutes to Fitness: Dr. Ben’s Smart Plan for Diet and Total Health, outlines a sensible and rational approach to diet and exercise. Bocchicchio’s method produces significant results by working with physiology and it is a must-read for fitness and health professionals. Bocchicchio discusses his early years as a serious athlete and the fitness experts who influenced his journey. He talks about the history of health and fitness and the struggle to bring good fitness ideas into mainstream consciousness.
The fitness guru discusses the development of his celebrated slow resistance training techniques known as ‘smart training.’ He describes his program as high intensity and it has garnered successful results for many of his clients and followers, from elite athletes to the average health-conscious person. As he details, his program requires just two 15-minute sessions per week to see a real impact on health and energy, as well as increase of metabolism. Bocchicchio provides insight on his thoughts behind the development of the smart training techniques. Bocchicchio states that he wanted to look at how our earlier ways of living impacted good health. He talks about how early humans did not have carbohydrates but had to exist on fish and fowl that required humans to hunt, which was an intensive workout.
Bocchicchio provides some detailed information on insulin resistance and the negative impact of carbohydrates, and how our bodies truly don’t need them. He describes the process of fat cell storage, and how the prevalence of sugar in so many of our foods is leading to health problems. Essentially, Dr. Bocchicchio states that the consumption of carbohydrates is akin to ingesting insulin. And while a full diet and exercise plan is the best option, simply cutting carbohydrates is one step that everyone can take for their health. And Bocchicchio goes in-depth about the methods our bodies use to burn fat and sugar, and how fasting can provide an opportunity for the body to initiate an intensive energy burning process. When we eat, as Bocchicchio states, we are sending a metabolic signal to our bodies to store energy, and when we fast we are telling our bodies to burn energy. He outlines how intermittent fasting can be an option for people who want to stimulate their burn.
Bocchicchio details the many types of exercise and workout plans that people invest their time into, and he stresses the importance of high-intensity exercise because it releases adrenaline, which in turn forces the body to release stored fat. He explains that steady state cardio exercise is good for overall health but that it will not change one’s metabolic status or make the body leaner. He states that in order to achieve the best results for metabolic purposes, essentially pushing the body to burn more energy, that we must work harder at a high-intensity level, which can only be done in short blocks of time due to the intensity it requires.
The diet and fitness expert delivers an intensive overview of other factors that drive insulin resistance and the dangers of sugar loading. He talks about exercise techniques and gives specific examples of methods that everyone can use to improve their exercise regimens and general health. He discusses safe, productive, and intermittent exercising and the benefits of keeping a regular routine. Bocchicchio explains his personal workout routine and the advantages of working each set of muscles to failure, thus pushing the workout to a high-intensity level that maximizes the metabolic benefits. And he wraps up his thorough analysis of health and fitness by discussing some of his partnerships with various fitness groups and brands, as well as the tools one can use to exercise efficiently and intensely, for optimum health.
Rank #15: The Most Healthful Diet, or an Exercise in Irrational Exuberance--Valter D. Longo, PhD--Biogerontologist, Cell Biologist, and Author of The Longevity Diet
The ketogenic diet, intermittent fasting, whether or not you should skip that first meal of the day...you’ve probably heard a lot of arguments for and against each, so how do you know what’s “right”? What will provide YOU with healthful longevity? Valter D. Longo is a biogerontologist, cell biologist, and author of several books, the latest of which is The Longevity Diet. He joins the podcast to discuss his views on these issues and shed light on some of the main arguments in his book, each of which is based on the scientific evidence that’s available today.
The Longevity Diet is divided into two sections: the first utilizes an approach that’s based in part on findings of epidemiological and clinical studies to decide how best to eat on a daily basis, and the second discusses the benefits of the fasting mimicking diet. He’s a proponent of diets rich in legumes and vegetables, 12-hour daily fasts, and making time for breakfast each morning.
While he admits that the ketogenic diet may benefit some individuals with particular health issues or diseases, he references a Harvard study that followed 120 subjects over a 30-year span and drew conclusions about the long-term effects of high fat, high protein, low carb diets: significantly shorter lifespans, and higher rates of cancer and cardiovascular disease. He also discusses how daily fasts that exceed 12 hours lead to a mechanism by which the body essentially begins eating itself, and how the concept of “irrational exuberance” is largely at play in many people’s devotion to diet fads.
Rank #16: Understanding Biological Meaning, Biological Versus Artificial Intelligence, and Evolutionary Agency—Victoria N. Alexander—Dactyl Foundation, Author of The Biologist's Mistress
“In biosemiotics, we say that the human ability to interpret signs—which is the ability to think really, to think creatively and adaptively and learn new things—didn’t just emerge with animals; rudimentary sign reading emerged in the simplest forms of life with single-celled organisms,” says Victoria Alexander, biosemiotician, Director of Dactyl Foundation, Fulbright specialist, and author of The Biologist's Mistress: Rethinking Self-Organization in Art, Literature, and Nature.
What’s biosemiotics, you ask? Alexander explains biosemiotics as the study of sign use in biological systems, where signs can be almost anything in the environment—a word, a pictogram, a smell, a sound, or a chemical gradient. Signs are intelligence; we can train a computer to read signs, but can we train a computer to interpret signs that depend on the context within which they exist?
Answering this question is one aspect of the investigation into the differences between biological and artificial intelligence, which is what Alexander’s work is currently focused on. She explains that biological cells don’t just react to the chemistry around them, but interpret and respond to it.
She goes on to explain how this underlies a system of interpretation that's related to random change in a way that’s changing the direction of evolution. In this way, Alexander argues that it is within the organism that evolutionary agency is found and explained, rather than in the mechanisms of randomness and competition.
Alexander offers an exciting and informative conversation that touches on a variety of topics, including metabolic pathways, the association of properties and the placebo effect, the idea that dysfunctional semiotic habits are the cause of some syndromes and conditions, cell differentiation, self-organization in nature, and butterfly wing pattern development. Press play to hear the full conversation.
Rank #17: Helping You Achieve a State of Ketosis in a Day, and Maintain it Continuously—Gary Millet—Kegenix
Have you been interested in trying a keto diet, but had trouble getting going and sticking with the strict rules? Or maybe you’re just worried about the infamous “keto flu.” Gary Millet, founder of Kegenix, joins the podcast to discuss a way around these challenges: by consuming exogenous ketones in liquid form and simply reducing your carb intake, you can enter a state of ketosis within a matter of an hour, making the path forward much easier.
The team at Kegenix has combined MCT oil and ketone salts into a substance that not only delivers exogenous ketones but also stimulates your body’s own ability to produce ketones—extending the state of ketosis far beyond what you’d get by just taking ketone salts. They’ve also created the first ketone meal replacement that not only contains all of the macro-nutrients and vitamins that a keto meal would have, but can be made into pancakes, waffles, biscuits, and more. In the works are products designed to specifically address different goals, such as weight loss or increased and sustained energy.
Millet touches on a range of interesting topics, including the important difference between ketone esters and ketone salts, what’s really happening in the body when people experience the “keto flu” and why exogenous ketones can help you avoid it, and what happens when the body uses ketones as fuel versus glucose as fuel.
Tune in for all the details and check out realketones.com for more info.
Rank #18: The 3D Metal Movement – Jonah Myerberg, Co-founder and CTO of Desktop Metal – How 3D Metal Printing Is Improving Quality and Efficiency in the World of Manufacturing and Mechanical Engineering
Jonah Myerberg, co-founder and CTO of Desktop Metal (desktopmetal.com), discusses the current state of technology in 3D printing and how it is revolutionizing engineering and manufacturing. Myerberg oversees the technical direction of Desktop Metal’s 3D printing solutions. He founded Boston Impact, an engineering consulting firm, in 2013, and has worked at the top level of many successful businesses focused on high-performance battery development, including Renovo Auto and A123Systems.
During his tenure with A123Systems, Myerberg helmed the motorsports business unit that focused primarily on the development of high-performance batteries that were later adopted by many leading Formula One teams such as McLaren, Force India, Mercedes Benz, and Red Bull. Additionally, he was a race engineer for Porsche on their 919 teams and also for Mahindra Racing on the Formula E team. Myerberg has a bachelor’s degree in mechanical engineering from Lehigh University, as well as a master’s degree in mechanical engineering and manufacturing from the prestigious Johns Hopkins University.
Myerberg states that his primary goal is to make metal 3D printing more accessible to manufacturers and engineers. Myerberg’s company, Desktop Metal, specializes in bringing new capabilities to the world’s first office-friendly, metal 3D printing solution. They provide high-resolution printing that can be in-house and built to exact specifications and scale. Desktop Metal’s Studio System abandons the traditional lasers and loose powders typically associated with metal 3D printing, which allows for higher safety standards. And businesses appreciate that power and an internet connection can get them going, simply and efficiently, without third-party equipment.
Myerberg compares and contrasts plastics 3D printing and metal 3D printing and details the variables with both, outlining polymer printing techniques for plastics versus the solid-state techniques needed for metal printing. He explains how his company has taken advantage of polymer techniques to bring that technology to the office environment for metal 3D printing.
The 3D printing and engineering specialist expounds upon the technical manufacturing knowledge that is needed in the mechanical engineering world. He discusses the new tools that are being utilized specifically for 3D printing, such as Desktop Metal’s Live Parts, which is proprietary software they developed that allows engineers to input their specifications and constraints in order to allow the software to actually grow the part between the holding points, establishing the geometry via the software. This saves time and creates a very efficient process as engineers can spend more of their day on engineering tasks, and less time on solving parts problems.
Myerberg lists some of the many advantages of 3D metal printing, such as reduction of total number of parts by streamlining the geometry, and significant decreases in the weight of parts overall by utilizing layer construction and other methods. And Myerberg provides his insight into the future of 3D metal printing. He gives examples of some of the companies they work with who are helping to drive the technology forward as they collaborate.
Rank #19: On the Future of Digital Storage and Synthetic DNA—Thomas Coughlin—Coughlin Associates
As the president of Coughlin Associates, Thomas Coughlin is a widely-respected digital storage analyst and business and tech consultant with over 35 years’ worth of experience in the data storage engineering industry. He also has six patents under his name and is the author of Digital Storage in Consumer Electronics: The Essential Guide. On today’s episode, he discusses the future of digital storage technology, which may very well lie in the strands of synthetic DNA. He explains that DNA can store a high density of information, with a potential capacity 1,000 times greater than what’s currently achievable with modern storage technology like hard drives. He explains what it will take to get there, the challenges that must be overcome, and a rough timeframe for when DNA-based data storage could become commercialized and mainstream.
In addition, Coughlin talks about a number of fascinating topics, including the work being done towards using microfluidic silicon matrices as storage devices, technology obsolescence, neuromorphic computing, brain to electronics interfaces, artificial telepathy, deepfake technology, and the legal and ethical implications of these emerging capabilities. Tune in for all the details, including info about an August 29th conference on emerging memories and AI.
Rank #20: Long, Beautiful Hair – Hasan Erbil Abaci, Assistant Professor at Columbia University Medical Center – New Discoveries, Hair Follicles and Hair Growth
Hasan Erbil Abaci, Assistant Professor at Columbia University Medical Center, delivers an extensive overview of tissue engineering, specifically in regard to hair follicles.
Abaci has published his work in many areas of scientific research including the following: Tissue engineering of human hair follicles using a biomimetic developmental approach, Human Skin Constructs with Spatially Controlled Vasculature Using Primary and iPSC-Derived Endothelial Cells, Human-on-a-chip design strategies and principles for physiologically based pharmacokinetic/pharmacodynamic modeling, and many more.
Abaci discusses skin, a very complex organ composed of many different components that goes much deeper than simply the dermis and epidermis we typically think of. He talks about how hair follicles are connected, and how they are very complex organs themselves. Abaci describes how hair follicles function and how they communicate with other tissues in the skin, such as the blood vessels, for example. He explains how cells within the skin system can signal, and how tissues regenerate. Abaci talks about hair follicles, in regard to their growth cycle, and how this process requires newly formed blood vessels and a custom supply of blood.
Abaci explains the geometry. He explains in detail how they work with their samples in the lab, providing information on their use of 3D printed molds with hair follicle extensions embedded. He discusses the hydrogel that forms around the hair follicle-like extensions, and how they work with this process to explore the open channels that now have the geometry of actual hair follicles.
Abaci discusses what we know and don’t know about the chemical and physical signaling within the body. But if researchers can decipher how some of these processes work it may be possible to recreate signals in vitro, then scientists will have insight into how to grow hair follicles efficiently—in vitro. And as Abaci explains, this—is the crux of true tissue engineering.