Rank #1: Ep 26 Vaccines part 1: Let's hear it for Maurice
The wait is finally over: this week we are very excited to bring you the episode we’ve been teasing for weeks: vaccines! This week and next (you don’t have to wait a full two weeks for the next episode!), we are presenting a two-part series on vaccines. In today’s episode, we dive deep into the biology of vaccines, from how they stimulate your (amazing) immune system to protect you, to how they make you into an almost-superhero, shielding the innocents around you from deadly infections. We take you back hundreds, nay, thousands of years to when something akin to vaccination first began, and then we walk along the long road of vaccine development to see just how massive an impact vaccines have had on the modern world. The best part? We are joined by not one, but two experts from the Bill and Melinda Gates Foundation. Dr. Gail Rodgers and Dr. Padmini Srikantiah explain the process of vaccine development, highlight the challenges of vaccine deployment, and shine a hopeful light on the future of vaccines. And be sure to tune in next week for part 2 where we’ll focus on vaccine hesitancy and address common misconceptions surrounding vaccines in even more depth.
For more information on the Bill and Melinda Gates Foundation initiatives, visit: https://www.gatesfoundation.org/
For more information on vaccines currently in development, check out: https://clinicaltrials.gov/ and https://www.who.int/immunization/research/vaccine_pipeline_tracker_spreadsheet/en/
And, as always, you can find all of the sources we used in this episode on our website: http://thispodcastwillkillyou.com/episodes/
Rank #2: Ep 5 Plague Part 1: The GMOAT
Rank #3: Ep 3 Gnarlypox
Rank #4: Ep 14 Rabies: Don't dilute me, bro
After a long hiatus we are back with a much anticipated look at one of the most feared diseases of all time: rabies. We cover everything from its evolutionary history to its massive case fatality rate, from why it makes you slobber so much to how Pliny the Elder thought you should treat it (spoiler: don't try it at home, folks). Sit back with a foam-topped quarantini in hand and enjoy our first episode of season 2.
Rank #5: Ep 15 MRSA: Make Resistance Susceptible Again
We've gotten pretty graphic on this podcast before, but this episode takes it to a whole new level. The omnipresent Staphylococcus aureus is a bacterium that wears many faces. Often that face is harmless, but Staph has the power to invade and infect nearly every organ of the body, leaving destruction (and a lot of pus) in its wake. While Staphylococcus aureus has been wreaking havoc on humans since well before the discovery of antibiotics, Methicillin-resistant Staph aureus (MRSA) has risen to terrifying prominence as resistance becomes the new norm. If any disease could make you run out (or stay in) and wash your hands, it’s this one. As always, you can find all of our sources at thispodcastwillkillyou.com/episodes.
Rank #6: Ep 21 Measles: The Worst Souvenir
You’ve seen the recent headlines and heard the news reports, but they’re only part of this deadly virus’s story. This week we’re covering the rest. We take you on a one-of-a-kind tour of measles, exploring how this vaccine-preventable virus can wriggle its way into your cells and cause short-term misery and long-term damage. Then we trace the history of this notorious killer from its bovine beginnings to the devastation it wreaked on unexposed populations. The tour ends with a look at measles by the numbers around the world today. If you take home one souvenir from this tour, let it be gratitude for vaccines!
Rank #7: Ep 4 The Poop Show
That's right.. this is the poop show! Today we talk cholera- the bacterial disease that makes you liquid-poop your pants (and then some). Travel back in time with us to when London was a sewage-filled cesspool until the Original John Snow stepped in to save the day and created the field of epidemiology. But is cholera a thing of the past? Not so much.
Rank #8: Ep 25 Put your hands together for: Gonorrhea!
This bug deserves a big round of applause and not just because it’s nicknamed “The Clap”. Check out this week’s episode to gasp in wonder at the tricks that Neisseria gonorrhoeae uses to tiptoe past your immune system. Then prepare to cringe at some old-timey treatments for the disease while we trace the history of this ancient pathogen. Finally, make sure you have a quarantini or placeborita in hand for when we chat about the not-so-cheery outlook for this particular sexually-transmitted infection. Believe us, this is one episode you’re not gonn(orrhe)a want to miss.
Rank #9: Ep 11 Ebola: The New Kid on the Block
Rank #10: Ep 12 HIV/AIDS: Apathy Will Kill You
Don’t forget to tune in next week for our special bonus episode where you will get to hear more of Frank, Hillel, and Brryan's stories in depth. In the meantime, here are a couple of links to Brryan's website and Being Alive LA which you'll hear more about next week!
Rank #11: Ep 20 Prions: Apocalypse Cow
This week's episode is nothing like any of our past episodes, and there will never be another quite like it. How can we be so sure, you ask? Because this week, we're covering prions, the terrifying, genetic material-less infection that is 100% fatal and caused by nothing more than a humble protein. And not just any protein, a protein you already have in your body. Are you sweating yet? Good. Then settle in and listen to the amazing biology of this terrifying twisted proteinacious particle, the fascinating and fraught history that led to its discovery, and the current research on just how scared you need to be of prions in your brain.
Rank #12: Ep 19 Scurvy: Thanks a lot, evolution.
Arr, mateys, climb aboard for a swash-buckling tale of when the high seas were full of disease! Today we’re covering a non-infectious but no less terrifying scourge that has wrecked millions of lives and sent even the bravest of sailors quivering in their boots: Scurvy. From the open ocean to the California gold rush to modern times, scurvy has been causing collagen breakdown throughout human history, and we can blame it all on...evolution?