Cover image of Smart Drug Smarts: Brain Optimization | Nootropics | Neuroscience

Smart Drug Smarts: Brain Optimization | Nootropics | Neuroscience

Fuel Your Brain With the Latest in Neuroscience

Ranked #1

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#155: Microdosing LSD with Dr. James Fadiman

#155: Microdosing LSD with Dr. James Fadiman

Here’s why psychedelics aren’t just a hippy phenomenon. The post #155: Microdosing LSD with Dr. James Fadiman appeared f... Read more

19 Nov 2016

50mins

Ranked #2

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#098: Adderall Perspectives

#098: Adderall Perspectives

In episode #98 Jesse throws four prescribed Adderall users into the mix who talk about their experiences with the drug a... Read more

16 Oct 2015

30mins

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Ranked #3

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#040: A Nootropics Roundtable

#040: A Nootropics Roundtable

Jesse and two guests discuss some popular misconceptions about smart drugs, their personal favorite stacks, and other to... Read more

29 Jun 2014

46mins

Ranked #4

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#129: LSD With Dr. Robin Carhart-Harris

#129: LSD With Dr. Robin Carhart-Harris

Jesse talks with Dr. Carhart-Harris about the prototypical psychedelic, LSD, how it changes the brain in long-lasting wa... Read more

20 May 2016

46mins

Most Popular Podcasts

Ranked #5

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#046: Improving on Piracetam with Noopept

#046: Improving on Piracetam with Noopept

Dr. Rita Ostrovskaya, world-leading expert and co-creator of Noopept, joins us to shed some light on this new-to-the-sce... Read more

21 Sep 2014

22mins

Ranked #6

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#082: Lion’s Mane Mushroom

#082: Lion’s Mane Mushroom

Tune in to our first ever fungal episode where Eric Cerecedes joins Jesse for a wildly interesting conversation about Li... Read more

27 Jun 2015

39mins

Ranked #7

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#137: DMT: Dr. Rick Strassman’s Breakthrough Work With “The Spirit Molecule”

#137: DMT: Dr. Rick Strassman’s Breakthrough Work With “The Spirit Molecule”

Dr. Rick Strassman is something of a legend in the psychedelic research community. His studies in the early 1990s re-op... Read more

15 Jul 2016

56mins

Ranked #8

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#113: Porn Addiction and the Brain

#113: Porn Addiction and the Brain

The fallout from porn addiction goes beyond sexual dysfunction -- way beyond. The brain's dopamine system is the major ... Read more

30 Jan 2016

50mins

Ranked #9

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#221: Marijuana, the Non-Medical Kind ;)

#221: Marijuana, the Non-Medical Kind ;)

It's easier to smoke marijuana legally these days than it is to study it. Strange, but true. But with tens of millions... Read more

9 Mar 2018

1hr 4mins

Ranked #10

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#147: Ketosis and Your Brain

#147: Ketosis and Your Brain

Remember when carbs were good and fat was evil? Now, not so much. Here's why (and how) you should try ketosis. The post ... Read more

23 Sep 2016

1hr 9mins

Ranked #11

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#074: Know Your Neurotransmitters: Dopamine

#074: Know Your Neurotransmitters: Dopamine

Round 2 of the “Know Your Neurotransmitters” series, featuring Professor John Salamone of the University of Connecticut,... Read more

1 May 2015

33mins

Ranked #12

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#039: Dr. Emily Deans Explains Ketosis

#039: Dr. Emily Deans Explains Ketosis

Dr. Emily Deans Explains Ketones and the State of Ketosis The post #039: Dr. Emily Deans Explains Ketosis appeared first... Read more

16 Jun 2014

35mins

Ranked #13

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#118: Turmeric: Spice for your Brain

#118: Turmeric: Spice for your Brain

The adaptogen plant turmeric has been a mainstay of Indian and Asian cooking for millenia. Its root is chock-full of bi... Read more

5 Mar 2016

45mins

Ranked #14

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#057: Rhodiola rosea: “Santa’s Stimulant”

#057: Rhodiola rosea: “Santa’s Stimulant”

Dr. Patricia Gerbarg introduces us to Rhodiola rosea, an herbal supplement used to increase stamina, decrease mental fat... Read more

22 Dec 2014

42mins

Ranked #15

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#105: The Racetam Family

#105: The Racetam Family

Whether you’re complete strangers or bosom buddies with the Racetam family, Jesse and Dr. Andrew Hill will make you feel... Read more

4 Dec 2015

33mins

Ranked #16

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#120: Intermittent Fasting and Cognition with Dr. Mark Mattson

#120: Intermittent Fasting and Cognition with Dr. Mark Mattson

Dr. Mark Mattson, neurologist at Johns Hopkins University and the National Institute of Health (NIH), has decades of wor... Read more

18 Mar 2016

42mins

Ranked #17

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#177: Know Your Neurotransmitters: Acetylcholine

#177: Know Your Neurotransmitters: Acetylcholine

It’s high time we covered acetylcholine — the most plentiful neurotransmitter in the body.  And our Know Your Neurotrans... Read more

21 Apr 2017

40mins

Ranked #18

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#116: Psilocybin and the Potential for “Psychedelic Therapies”

#116: Psilocybin and the Potential for “Psychedelic Therapies”

Dr. Frederick Barrett discusses recent and upcoming studies into psilocybin -- the psychoactive ingredient that puts the... Read more

19 Feb 2016

36mins

Ranked #19

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#125: Exercise and Cognition

#125: Exercise and Cognition

Brains and Brawn, long positioned as polar opposites, turn out to be anything but. In this episode, Jesse talks with fi... Read more

22 Apr 2016

48mins

Ranked #20

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#199: The MIND Diet with Dr. Martha Morris

#199: The MIND Diet with Dr. Martha Morris

The "MIND Diet" makes a strong claim in its very name. Is it the best nutritional strategy to prevent the onset of Alzh... Read more

23 Sep 2017

44mins

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