Ranked #1
#155: Microdosing LSD with Dr. James Fadiman
#155: Microdosing LSD with Dr. James Fadiman
Here’s why psychedelics aren’t just a hippy phenomenon. The post #155: Microdosing LSD with Dr. James Fadiman appeared f... Read more
19 Nov 2016
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50mins
Ranked #2
#098: Adderall Perspectives
#098: Adderall Perspectives
In episode #98 Jesse throws four prescribed Adderall users into the mix who talk about their experiences with the drug a... Read more
16 Oct 2015
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30mins
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Ranked #3
#040: A Nootropics Roundtable
#040: A Nootropics Roundtable
Jesse and two guests discuss some popular misconceptions about smart drugs, their personal favorite stacks, and other to... Read more
29 Jun 2014
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46mins
Ranked #4
#129: LSD With Dr. Robin Carhart-Harris
#129: LSD With Dr. Robin Carhart-Harris
Jesse talks with Dr. Carhart-Harris about the prototypical psychedelic, LSD, how it changes the brain in long-lasting wa... Read more
20 May 2016
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46mins
Ranked #5
#046: Improving on Piracetam with Noopept
#046: Improving on Piracetam with Noopept
Dr. Rita Ostrovskaya, world-leading expert and co-creator of Noopept, joins us to shed some light on this new-to-the-sce... Read more
21 Sep 2014
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22mins
Ranked #6
#082: Lion’s Mane Mushroom
#082: Lion’s Mane Mushroom
Tune in to our first ever fungal episode where Eric Cerecedes joins Jesse for a wildly interesting conversation about Li... Read more
27 Jun 2015
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39mins
Ranked #7
#137: DMT: Dr. Rick Strassman’s Breakthrough Work With “The Spirit Molecule”
#137: DMT: Dr. Rick Strassman’s Breakthrough Work With “The Spirit Molecule”
Dr. Rick Strassman is something of a legend in the psychedelic research community. His studies in the early 1990s re-op... Read more
15 Jul 2016
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56mins
Ranked #8
#113: Porn Addiction and the Brain
#113: Porn Addiction and the Brain
The fallout from porn addiction goes beyond sexual dysfunction -- way beyond. The brain's dopamine system is the major ... Read more
30 Jan 2016
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50mins
Ranked #9
#221: Marijuana, the Non-Medical Kind ;)
#221: Marijuana, the Non-Medical Kind ;)
It's easier to smoke marijuana legally these days than it is to study it. Strange, but true. But with tens of millions... Read more
9 Mar 2018
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1hr 4mins
Ranked #10
#147: Ketosis and Your Brain
#147: Ketosis and Your Brain
Remember when carbs were good and fat was evil? Now, not so much. Here's why (and how) you should try ketosis. The post ... Read more
23 Sep 2016
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1hr 9mins
Ranked #11
#074: Know Your Neurotransmitters: Dopamine
#074: Know Your Neurotransmitters: Dopamine
Round 2 of the “Know Your Neurotransmitters” series, featuring Professor John Salamone of the University of Connecticut,... Read more
1 May 2015
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33mins
Ranked #12
#039: Dr. Emily Deans Explains Ketosis
#039: Dr. Emily Deans Explains Ketosis
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16 Jun 2014
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35mins
Ranked #13
#118: Turmeric: Spice for your Brain
#118: Turmeric: Spice for your Brain
The adaptogen plant turmeric has been a mainstay of Indian and Asian cooking for millenia. Its root is chock-full of bi... Read more
5 Mar 2016
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45mins
Ranked #14
#057: Rhodiola rosea: “Santa’s Stimulant”
#057: Rhodiola rosea: “Santa’s Stimulant”
Dr. Patricia Gerbarg introduces us to Rhodiola rosea, an herbal supplement used to increase stamina, decrease mental fat... Read more
22 Dec 2014
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42mins
Ranked #15
#105: The Racetam Family
#105: The Racetam Family
Whether you’re complete strangers or bosom buddies with the Racetam family, Jesse and Dr. Andrew Hill will make you feel... Read more
4 Dec 2015
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33mins
Ranked #16
#120: Intermittent Fasting and Cognition with Dr. Mark Mattson
#120: Intermittent Fasting and Cognition with Dr. Mark Mattson
Dr. Mark Mattson, neurologist at Johns Hopkins University and the National Institute of Health (NIH), has decades of wor... Read more
18 Mar 2016
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42mins
Ranked #17
#177: Know Your Neurotransmitters: Acetylcholine
#177: Know Your Neurotransmitters: Acetylcholine
It’s high time we covered acetylcholine — the most plentiful neurotransmitter in the body. And our Know Your Neurotrans... Read more
21 Apr 2017
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Ranked #18
#116: Psilocybin and the Potential for “Psychedelic Therapies”
#116: Psilocybin and the Potential for “Psychedelic Therapies”
Dr. Frederick Barrett discusses recent and upcoming studies into psilocybin -- the psychoactive ingredient that puts the... Read more
19 Feb 2016
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36mins
Ranked #19
#125: Exercise and Cognition
#125: Exercise and Cognition
Brains and Brawn, long positioned as polar opposites, turn out to be anything but. In this episode, Jesse talks with fi... Read more
22 Apr 2016
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48mins
Ranked #20
#199: The MIND Diet with Dr. Martha Morris
#199: The MIND Diet with Dr. Martha Morris
The "MIND Diet" makes a strong claim in its very name. Is it the best nutritional strategy to prevent the onset of Alzh... Read more
23 Sep 2017
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44mins