Rank #1: The Motility of the Gut: What Do We Know?
Host: Mark DeLegge, MD
What is the underlying mechanism of propulsion in the digestive system, and how is motility stimulated? How are some newer pharmacotherapies looking to target serotonin to treat conditions such as IBS and constipation? Dr. Jack Grider, professor in the department of medicine, division of gastroenterology at the Virginia Commonwealth University School of Medicine, talks about future pharmacotherapy directions that either suppress or encourage motility in the digestive system. Hosted by Dr. Mark DeLegge.
Aug 04 2009
Rank #2: Diet & Nutrition in the Management of IBD
Guest: James D. Lewis, MD, MSCE
Whether they’re not getting enough calories or not eating a balanced diet due to disease restrictions, patients with IBD often have difficulty maintaining a healthy diet. So how can you help them navigate these diet and nutrition challenges?
Filmed live at the 2018 Crohn's and Colitis Evening of Hope, Dr. James Lewis from the University of Pennsylvania discusses strategies you can implement in your practice.
Mar 18 2019
Rank #3: The Many Faces of Irritable Bowel Syndrome: Multimodal Treatments for a Complex Disease
Irritable bowel syndrome is becoming increasingly recognized as a complex interplay of pathologies, from changes in gut microflora to nutrient absorption abnormalities to psychosocial stressors. The ways in which these factors contribute and interact create different profiles of disease, requiring personalized therapeutic plans for IBS patiets. Joining Dr. Barry Mennen to discuss a multimodal model for approaching the root causes of IBS is Dr. Neelesh A. Tipnis, the Paul H. Parker Professor and Chair of Pediatric Gastroenterology and Director of the GI Motility and Functional Bowel Disorders Program at the University of Mississippi Medical Center.
Aug 10 2015
Rank #4: IBS and Functional GI Disorders (FGIDs)
Guest: Douglas Drossman, MD
Host Dr. Jay Goldstein discusses the latest in IBS & Functional GI Disorders (FGIDs) with guest expert Dr. Douglas Drossman of the Drossman Center for the Education and Practice of Integrated Care. Dr. Drossman is Professor Emeritus in the departments of Gastroenterology and Psychiatry at the Center for Functional GI and Motility, University of North Carolina at Chapel Hill.
Apr 27 2015
Rank #5: Can Dietary Zinc Help Treat and Prevent Inflammatory Bowel Disease?
Host Dr. Barry Mennen welcomes Dr. Ashwin Ananthakrishnan, Assistant Professor of Medicine at Harvard Medical School and medical co-director at the MGH Crohn’s and Colitis center. Dr. Ananthakrishnan is involved in several large cohort studies that are attempting to examine established and novel environmental factors, including diet, that influence the risk of development of inflammatory bowel diseases. His recent study focusing on the potential role of dietary zinc in preventing bowel inflammation becomes the focus of this discussion.
Oct 26 2015
Rank #6: When PPIs Fail: Evaluating and Managing Patients with Refractory GERD
Host: Lee Freedman, MD
Resistance to proton pump inhibitors, or PPIs, is not uncommon among patients with gastroesophogeal reflux disease, or GERD. How should physicians initially approach managing patients with suspected GERD, and at what point should physicians classify a patient as a PPI non-responder? Our guest, Dr. Brian Lacy, associate professor of medicine at Dartmouth Medical School, and director of the GI Motility Laboratory at Dartmouth-Hitchcock Medical Center in Lebanon, New Hampshire, suggests tests that physicians might use in evaluating patients with refractory GERD, including upper endoscopy and various types of pH monitoring. What therapeutic strategies can physicians use to manage these patients? Hosted by Dr. Freedman.
Sep 16 2010
Rank #7: Crohn's Disease: Latest Diagnosis, Treatment & Management Strategies
Host Dr. Jay Goldstein welcomes Dr. Sunanda V. Kane, Professor of Medicine in the Department of Gastroenterology & Hepatology at Mayo Clinic, to dicuss the latest in Crohn's disease diagnosis and management. Dr. Kane is author of IBD Self-Management: The AGA Guide to Crohn's Disease and Ulcerative Colitis, now in its second edition.
Apr 20 2015
Rank #8: Novel Perspectives on Inflammatory Bowel Disease: Focus on Microbiomes and Stool Transplants
Live from the floor of Digestive Disease Week in Washington DC, GI Insights presents two interviews focusing on innovative approaches to inflammatory bowel disease, hosted by Dr. Barry Mennen. Guests on this program include:
- Dr. Jonathan Braun, Professor and Chair of Pathology and Lab Medicine at the David Geffen School of Medicine at UCLA. His research centers on the biology of mucosal interaction of host immunity with the local microbial community, and its impact on chronic mucosal inflammatory disease and cancer.
- Michael Hurst, author of Poop Power: How a Man Used a Fecal Transplant at Home to Permanently Cure Himself of Ulcerative Colitis. Mr. Hurst is a known advocate and volunteer for the Fecal Transplant Foundation, whose story of self-designing an unorthodox treatment regimen for ulcerative colitis has since offered new insights on best clinical management practices for IBD.
Jul 27 2015
Rank #9: IBS-D: A Case Study Approach to Improved Screening & Detection
IBS is a common disorder affecting 10% to 15% of the adult population. IBS-D can be diagnosed using symptom-based criteria, a detailed physical exam, and select tests to exclude organic diseases. In this activity, clinicians will learn screening and detection methods for IBS-D, including ROME IV criteria, alarm features, and select tests such as complete blood count, C-reactive protein /stool calprotectin, tissue transglutaminase (IgA and IgG), stool analysis, and assessment for bile acid malabsorption.
Dec 14 2018
Rank #10: Reliability of Measuring Ileo-Colonic Disease Activity in Crohn's Disease by MR Enterography
Reliability of Measuring Ileo-Colonic Disease Activity in Crohn's Disease by Magnetic Resonance Enterography.
Vipul Jairath, MD, PhD, Ingrid Ordas, MD, PhD, Guangyong Zou, PhD, Julian Panes, MD, Jaap Stoker, MD, PhD, Stuart A Taylor, MD, Cynthia Santillan, MD, Karin Horsthuis, MD, Mark A Samaan, MD, Lisa M Shackelton, PhD, Larry W Stitt, MSc, Pieter Hindryckx, MD, PhD, Reena Khanna, MD, William J Sandborn, MD ,Geert D'Haens, MD, PhD, Brian G Feagan, MD, Barrett G Levesque, MD, and Jordi Rimola, MD, PhD
Magnetic resonance enterography is increasingly utilized for assessment of luminal Crohn's disease activity. The Magnetic Resonance Index of Activity and the London Index are the most commonly used outcome measures in clinical trials. We assessed the reliability of these indices and several additional items.
A consensus process clarified scoring conventions and identified additional items based on face validity. Four experienced radiologists evaluated 50 images in triplicate, in random order, at least 1 month apart, using a central image management system. Intra- and interrater reliability were assessed by calculating and comparing intraclass correlation coefficients.
Intrarater intraclass correlation coefficients (95% confidence intervals) for the Magnetic Resonance Index of Activity, London, and London "extended" indices and a visual analogue ...
Jan 29 2019
Rank #11: Comparative Effectiveness of Drug Therapies for Inflammatory Bowel Disease
Host Dr. Barry Mennen welcomes Dr. Ryan Stidham, Assistant Professor of Internal Medicine at the Inflammatory Bowel Diseases Center of the University of Michigan Health System, to discuss the current therapeutic landscape for IBD based on recent comparative clinical trials.
Jul 20 2015
Rank #12: Making Dollars and 'Sense' of Physician Quality Reporting Systems in Gastroenterology
Physician Quality Reporting Systems, or PQRS, are here to stay in clinical medicine. Within the field of gastroenterology, understanding the metrics of PQRS can make a substantial difference in the success of a practice. Joining host Dr. Barry Mennen to detail the ins and outs of PQRS in gastroenterology is Dr. Ziad Gellad, Assistant Professor of Medicine, Director of Quality in the Division of Gastroenterology, and Director of Clinical Improvement in the Department of Medicine at Duke University Medical Center.
Nov 02 2015
Rank #13: Accreditation and Patient Safety in Endoscopy
Host: Mark DeLegge, MD
Endoscopy is extremely safe when performed by a qualified gastroenterologist. What role does accreditation play in ensuring patient safety? What's the difference between the associations that accredit ambulatory surgery centers? Host Dr. Mark DeLegge discusses what GIs need to know about accreditation with Dr. Lawrence Kim, a practicing gastroenterologist at South Denver Gastroenterology in Colorado.
Oct 07 2008
Rank #14: Measuring Bowel Prep Efficacy: The Role of the Quality Assessment Scale
Guest: Jonathan Cohen, MD
Joining Dr. Sophie Balzora to discuss the different bowel preparation quality assessment scales available and the advantages of each is Dr. Jonathan Cohen, Clinical Professor of Medicine at NYU School of Medicine.
May 29 2019
Rank #15: Evaluating Performance: The Physician Quality Reporting Initiative
Host: Mark DeLegge, MD
The Physician Quality Reporting Initiative (PQRI) is a CMS-based program designed to help medical professionals measure performance outcomes in their practice. How does the PQRI define quality, and how can it provide more concrete measurements of quality? What do GI practices need to know when becoming involved in the PQRI? Mary Igo, MBA, CEO of Minnesota Gastroenterology, a GI practice based in St. Paul, and an expert in medical group management, assesses the pros and cons of implementing the PQRI system with host Dr. Mark DeLegge.
Oct 07 2008
Rank #16: Does Obesity Play a Role in the History of Inflammatory Bowel Diseases?
To assess whether obesity may affect natural history of inflammatory bowel diseases (IBD), we conducted an individual participant data (IPD) pooled analysis of placebo arms, using data from clinical trials of infliximab in IBD and using the Yale Open Data Access (YODA) Project.
We obtained IPD from 4 placebo-controlled trials of infliximab in adults with IBD (ACCENT-I and ACCENT-II; ACT-1 and ACT-2). Patients were categorized into quartiles based on body mass index (BMI) or weight at time of trial entry. Primary outcome was clinical remission (Crohn’s disease activity index [CDAI]<150, Mayo Clinic Score <3); secondary outcomes were clinical response and mucosal healing. Using multivariable logistic regression analysis, we compared association between quartiles of BMI (or weight) and achieving remission, after adjusting for sex, smoking, disease activity, and concomitant prednisone or immunomodulators.
We included 575 placebo-treated patients (mean age 38 years, 51.6% males, 16% obese). Obesity was not associated with odds of achieving clinical ...
Jun 19 2019
Rank #17: IBS-D: The Role of Pathophysiology in Assessment & Treatment
Patients with IBS-D may spend years before they are accurately diagnosed, with their symptoms often being labeled as psychosomatic. Considering the potential underlying cause of IBS-D can help guide diagnosis as well as the choice of appropriate treatment. In this activity, clinicians will learn screening methods and factors in the pathophysiology of IBS-D to more accurately diagnosis patients and select appropriate treatment, along with patient-clinician communication strategies that can improve outcomes.
Dec 14 2018
Rank #18: Optimizing the Effectiveness of Colonoscopy for Colorectal Cancer Prevention: Importance of Breaking Down Barriers
Guest: Carol A. Burke, MD, FACG, FASGE, AGAF, FACP
Colonoscopies are an essential procedure, however the effectiveness in detecting colorectal cancer depends heavily on the quality of a patient’s bowel preparation. Here to discuss why some patients choose to skip this preventive procedure and what you can do to help reduce the chances of poor bowel preparation with Dr. Sophie Balzora is Dr. Carol Burke, Vice Chair of the Department of Gastroenterology, Hepatology and Nutrition at the Cleveland Clinic.
May 29 2019
Rank #19: Crohn’s & Colitis Congress: Making Sense of IBD Care Guidelines
Guest: Marla Dubinsky, MD
Not every IBD patient fits into IBD care guidelines, which is why Dr. Gary Lichtenstein and Dr. Marla Dubinsky discuss the best ways to use these guidelines in your practice at the second annual Crohn’s & Colitis Congress in Las Vegas.
Apr 02 2019
Rank #20: Quality Outcomes for Endoscopy
Host: Mark DeLegge, MD
The outcomes for endoscopy can vary greatly, depending on the training and technique of the endoscopist. Dr. Peter Cotton, professor of medicine at the Digestive Disease Center at the Medical University of South Carolina, discusses the risks of endoscopy, and quality-control measures, from the establishment of benchmarks to voluntary report cards to ensure quality outcomes. Dr. Mark DeLegge hosts.
Oct 07 2008