OwlTail

Cover image of StemCells@Lunch Digested
Education

StemCells@Lunch Digested

Updated 15 days ago

Education
Read more

Keeping the public up to date with current research taking place in the stem cell research community. Listen to guest speakers discuss their work, how they got to where they are today and their hopes for the future of stem cell research. Hosted by King's College London Centre for Stem Cells & Regenerative Medicine.

Read more

Keeping the public up to date with current research taking place in the stem cell research community. Listen to guest speakers discuss their work, how they got to where they are today and their hopes for the future of stem cell research. Hosted by King's College London Centre for Stem Cells & Regenerative Medicine.

Cover image of StemCells@Lunch Digested

StemCells@Lunch Digested

Latest release on Nov 17, 2020

Read more

Keeping the public up to date with current research taking place in the stem cell research community. Listen to guest speakers discuss their work, how they got to where they are today and their hopes for the future of stem cell research. Hosted by King's College London Centre for Stem Cells & Regenerative Medicine.

Episode 123 - Prof Manuel Serrano - "Understanding aging can help treat other diseases."

Podcast cover
Read more
Today, Professor Manuel Serrano from the Institute for Research in Biomedicine in Barcelona is interviewed by PhD student Emily Read. Manuel has produced seminal work in the fields of tumour suppression, senescence, ageing and reprogramming. In this episode he talks about the link between senescence and regeneration, and how this can become disrupted in disease and ageing. He discusses how targeting senescent cells can prolong lifespan and reflects on the impactions of this on wider society.

To find out more about Manuel’s work please visit the following website: https://www.irbbarcelona.org/en/profile/manuel-serrano

Nov 17 2020

14mins

Play

Episode 122- Prof Matthias Lütolf - "Organoids give us a new window into human biology."

Podcast cover
Read more
Today, Professor Matthias Lütolf, Head of the Laboratory of Stem Cell Bioengineering at The École polytechnique fédérale de Lausanne is interviewed by PhD student Emily Read. Matthais talks about how scientists can begin to build human diseases in a dish using organoid technologies. He discusses the importance of understanding how physical factors can influence stem cell behaviour and how this can be studied with engineering approaches.

To find out more about Matthias’ work please visit the following website: https://people.epfl.ch/matthias.lutolf/bio?lang=en

Oct 27 2020

23mins

Play

Episode 121 - Prof Kevin Eggan - "Science progresses through replication, validation, extension"

Podcast cover
Read more
Today, Professor Kevin Eggan from the Department of Stem Cell and Regenerative Biology at Harvard University, is interviewed by PhD student Peter Harley. Kevin talks about the difficulties of studying neurodegenerative disorders and applying stem cell technologies to study motor neuron disease/ALS. He discusses why highlighting and understanding contradictory findings is an essential part of scientific research and the reliability of using mouse models to study ALS.

To find out more about Kevin’s work please visit the following website: https://hsci.harvard.edu/people/kevin-c-eggan-phd

Oct 21 2020

15mins

Play

Episode 120 - Prof Salvador Benitah - "I still have to sit down and learn new things"

Podcast cover
Read more
Prof Salvador Aznar Benitah, ICREA Research Professor at Institut de Recerca Biomèdica, is interviewed by PhD student Victoria Tsang. Salvador talks about his research understanding the molecular pathways that dictate stem cell behaviour, including his recent work on the role of dietary fats, and how this goes wrong in cancer. He talks about recent advances in the field of oncology and the challenges they pose to clinical translation.

For more information on Salvador's research follow this link:
https://www.icrea.cat/Web/ScientificStaff/salvador-aznar-benitah-408

Oct 13 2020

23mins

Play

Episode 119 - Prof Alfonso Martinez Arias - "The 21st Century is the Century of the Cell."

Podcast cover
Read more
Professor Alfonso Martinez Arias, professor of developmental mechanics in the department of genetics at the University of Cambridge, is interviewed by PhD student Alice Vickers. Alfonso discusses the applications, ethical considerations, legislation, and difficulties of progressing his research using embryonic stem cells as a model system for studying human development. He also looks back at the experiences and experiments that hooked him on answering the vital question of how a single cell becomes a whole organism.

For more information on Alfonso's research follow this link:
https://www.gen.cam.ac.uk/directory/alfonso-martinez-arias

Oct 09 2020

20mins

Play

Episode 118 - Prof Trepat - "The biggest questions of our generation are in life sciences"

Podcast cover
Read more
Professor Xavier Trepat, ICREA Research Professor at Institut de Bioenginyeria de Catalunya, is interviewed by PhD student Sebastiaan Zijl. Xavier talks about his work understanding how physical forces impact how cells grow, move and behave. He discusses the coolest experiment he has ever done and how lockdown has unexpectedly benefited his lab.

For more information on Xavier's research follow this link:
https://www.icrea.cat/Web/ScientificStaff/xavier-trepat-534

Sep 29 2020

13mins

Play

Episode 117 - Prof Peter Zandstra - "We are bringing technology and biology together"

Podcast cover
Read more
Professor Peter Zandstra, Director of the Michael Smith Laboratories at The University of British Columbia, is interviewed by Group Leader Dr Davide Danovi. Peter talks about his work understanding blood development from stem cells and how this can be used improve therapeutics for diseases such as leukaemia. He discusses his beginnings as a chemical engineer and how this has shaped his career path.

For more information on Peter's research follow this link:
https://www.msl.ubc.ca/people/dr-peter-zandstra/

Sep 22 2020

12mins

Play

Episode 116 - Dr William Grey - Are proteins the key to understanding cancer?

Podcast cover
Read more
Dr William Grey, a post doctoral researcher in the Haematopoietic Stem Cell Laboratory at the Francis Crick Institute, is interviewed by PhD student Jana Obajdin. William talks about using umbilical cord blood in the treatment of genetic disorders and the future of cancer therapies. He also tells us why the study of proteins is an exciting and expanding field, particularity in cancer research.

For more information on William's research follow this link:
https://www.crick.ac.uk/research/find-a-researcher/william-grey

Donate your umbilical cord blood with Anthony Nolan:
https://www.anthonynolan.org/8-ways-you-could-save-life/donate-your-umbilical-cord

Sep 15 2020

12mins

Play

Episode 115 - Prof James Briscoe - Where does time come from in development?

Podcast cover
Read more
Prof James Briscoe, group leader of the Developmental Dynamics Lab at the Francis Crick Institute, is interviewed by PhD student Ieva Berzanskyte. James talks about his research into the developing spinal cord and thinks about what is currently fascinating him, including understanding the "tempo" of embryonic development.

For more information on James' research follow this link:
https://www.crick.ac.uk/research/labs/james-briscoe

Aug 26 2020

7mins

Play

Episode 114 - Prof Janet Rossant - "Science is going to get us out of this, science is the answer."

Podcast cover
Read more
Prof Janet Rossant, Senior Scientist on the Developmental & Stem Cell Biology Program, Chief of Research Emeritus at the SickKids Research Institute, President and Scientific Director of the Gairdner Foundation and Professor in the Departments of Molecular Genetics and Obstetrics & Gynaecology at the University of Toronto, is interviewed by PhD student Geraldine Jowett. Janet discusses her work characterising embryonic development and applying this to generate stem cell models. She talks about the importance of the terminology and language used surrounding embryo research, as well as how her lab is contributing to the COVID response.

For more information on Janet's research follow this link:
https://lab.research.sickkids.ca/rossant/

Aug 19 2020

16mins

Play

Episode 113 - Prof Olivier Pourquié - "I think pretty much every bit of Biology is interesting."

Podcast cover
Read more
"It’s a mindset."

Prof Olivier Pourquié, Professor of Pathology and Professor in the Department of Genetics at Harvard Medical School, is interviewed by PhD student Ella Hubber. Olivier breaks down how spinal vertebrae are formed in the embryo through a “segmentation clock” and how understanding this is relevant to human disease. He also talks about the significant changes in developmental biology over the course of his career.

For more information on Olivier's research follow this link:
https://hsci.harvard.edu/people/olivier-pourqui%C3%A9-phd

Aug 12 2020

13mins

Play

Episode 112 - Prof Cristina Lo Celso - "At the time stem cells seemed like the holy grail."

Podcast cover
Read more
Prof Cristina Lo Celso, Professor of Stem Cell Biology and group leader at Imperial College London, is interviewed by PhD student Elena Drudi. Cristina discusses her work visualising blood stem cells and determining the factors that control their function, to better understand mechanisms underlying blood based cancers. She also talks about her career progression and the importance for her of travelling between countries.

For more information on Cristina's research follow this link:
https://www.imperial.ac.uk/people/c.lo-celso

Aug 05 2020

11mins

Play

Episode 111 - Dr Ivo Lieberam - "How we are going to interact with technology in the long term?"

Podcast cover
Read more
We return this week to an episode recorded during lockdown.

Dr Ivo Lieberam, Senior Lecturer and group leader at the Centre for Stem Cells and Regenerative Medicine at King's College London, is interviewed by PhD student Eva Hamrud. Ivo discusses his work on generating neuromuscular models in a dish that can be used to understand neuromuscular diseases and screen novel therapies. He also discusses his long term aim to generate technologies, such as light controlled medical devices and biorobots, that could be used in the future to treat a range of diseases.

For more information on Ivo's research follow this link:
https://www.kcl.ac.uk/lsm/research/divisions/gmm/departments/stemcells/people/dr-ivo-lieberam

Jul 28 2020

17mins

Play

Episode 110 - Dr Francesca Spagnoli- "We study biological problems with direct medical application."

Podcast cover
Read more
We return this week with an episode recorded during lockdown.

Dr Francesca Spagnoli, Group Leader at the Centre for Stem Cells and Regenerative Medicine at King's College London, is interviewed by PhD student Teodora Manea. Francesca discusses her group's research on understanding how pancreatic beta cells communicate with their environment and the possibility of converting liver cells to pancreas cells, with the aim of applying this to cell replacement therapies in the treatment of diabetes. She also talks about studying mouse and human pancreatic development and learning from a comparative approach.

For more on Francesca's research, follow this link: https://www.spagnolilab.org/

Jul 22 2020

12mins

Play

Episode 109 - Prof James Sharpe - "You were limited by nothing but your own imagination."

Podcast cover
Read more
We return this week with an episode recorded during lockdown.

Prof. James Sharpe, the head of EMBL Barcelona, is interviewed by PhD student Sergi Junyent. Prof. Sharpe is one of the key opinion leaders in developmental biology and bioengineering. Here, he talks about the pioneering work done by his group in understanding tissue development and discusses his how his work brings together his passion for computer programming and biology.

For more information on Prof. Sharpe's research follow this link: https://www.embl.es/research/unit/sharpe/members/index.php?s_personId=CP-60027035

Jul 14 2020

13mins

Play

Episode 108 - Prof Jianping Fu - “Human development itself is just fascinating.”

Podcast cover
Read more
“Even just to understand the genesis of human being itself... It must be one of the holy grails of modern biology.”

We return this week with an episode recorded during lockdown.

Professor Jianping Fu, a professor of Mechanical Engineering, Biomedical engineering and Cell and Developmental Biology at the University of Michigan, is interviewed by PhD student Sergi Junyent. He talks about the technical difficulties and ethical issues of studying human development. He discusses the growing field of stem cell based embryo models to study the early stages of development and the future directions of these models.

For more information on Jianping's research follow this link: http://me-web.engin.umich.edu/ibbl/

Jun 30 2020

18mins

Play

Episode 107 - Prof Ludovic Vallier - "The drive is to generate more knowledge."

Podcast cover
Read more
We return this week with an episode recorded during lockdown.

Professor Ludovic Vallier, Professor of Regenerative Medicine within the Department of Surgery at Cambridge University and director of the National Institute for Health Research (NIHR) Cambridge Biomedical Research Centre hIPSCs (human induced pluripotent stem cells) core facility, is interviewed by PhD student Alice Vickers. He talks about his work using human pluripotent cells to generate pancreas, lung, gut and liver cells. He speaks about how his involvement in industry aims to generate cell types for clinical studies and for cell based therapy.

For more information on Ludovic's research follow this link:
https://www.stemcells.cam.ac.uk/People/pi/vallier

Jun 23 2020

17mins

Play

Episode 106 - Professor Peter Jones - "I think all scientists are curious by nature."

Podcast cover
Read more
We return this week with an episode recorded during lockdown.

Professor Peter Jones, Professor of Endocrine Biology and head of the Department of Physiology at King's College London, is interviewed by PhD student Prudence Lui. Peter breaks down the basics of type 1 and type 2 diabetes and discusses his lab's recent research into the phenomenon of mitochondrial transfer. After 36 years at King's, Peter talks about what has kept him in scientific research.

For more information on Peter's research follow this link:
https://www.kcl.ac.uk/people/peter-jones

Jun 16 2020

11mins

Play

Episode 105-Dr Norah Fogarty-"Understanding the placenta we may treat disease before manifestation"

Podcast cover
Read more
We return this week to an episode recorded during lockdown.

Dr Norah Fogarty, a new group leader at the Centre for Stem Cells and Regenerative Medicine at King's College London, is interviewed by PhD student Geraldine Jowett. Norah discusses her work on the development of the trophectoderm in the human embryo, which is the progenitor of early placental cells. She talks about how this work aims to further our understanding of human embryo development and early pregnancy loss, and may in the future lead to advances in assisted reproductive treatments.

For more information on Norah's research follow this link:
https://kclpure.kcl.ac.uk/portal/norah.fogarty.html

Jun 09 2020

12mins

Play

Episode 104 - Dr Alejo Rodriguez-Fraticelli - “What’s important is keeping an open mind.”

Podcast cover
Read more
Today on the SC@L Digested Podcast, Post-doc Miguel Bernabe-Rubio speaks with Alejo Rodriguez-Fraticelli, a research fellow at the Boston Children’s Hospital and soon-to-be principal investigator at the Institute for Research in Biomedicine in Barcelona. Alejo talks about his work using single cell maps to understand highly variable populations of cells and his future research focus on acute myeloid leukaemia. He also talks about developing his skills in computational biology through collaboration and the importance of stepping out of your comfort zone to succeed in interdisciplinary research.

To see more of Alejo's research, follow this link: https://connects.catalyst.harvard.edu/Profiles/display/Person/176343

Jun 02 2020

14mins

Play