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Personalized Diagnostics

Welcome to the Personalized Diagnostics Podcast.We are going to be talking to some of the greatest minds and personalities in the diagnostics space – the engine which is driving personalized medicine forward.We will be exploring the unmet need for better diagnostics across the patient journey - from screening to treatment to treatment monitoring, new assay development, technologies such as next generation sequencing and artificial intelligence plus we’ll be tackling issues in reimbursement and health economics- how we’re going to pay for all this and how diagnostics can provide value to the health care system.Thanks for listening.

Weekly hand curated podcast episodes for learning

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The best episodes ranked using user listens.

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Clifford Morris, PhD - Preview 1

"Metabolomics, we really see as the apogee of all the -omics."

1min

4 Feb 2020

Rank #1

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Roger Klein, MD JD, How are Molecular Diagnostcs Tests Reimbursed? - Episode 2

How exactly are molecular diagnostic tests reimbursed?Is our current coding and reimbursement system up to the task?How does a new test achieve reimbursement?Roger D. Klein, MD JD is a former HHS Advisor to FDA, CMS and CDC, and the immediate past chair of the Association for Molecular Pathology’s (AMP’s) Solid Tumors Division. A physician and an attorney, Dr Klein served as an expert and key spokesperson in the lawsuit “Association for Molecular Pathology v. Myriad Genetics, Inc.” in which the U.S. Supreme Court invalidated patents on breast cancer genes.

26mins

17 Dec 2019

Rank #2

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Michael Bonham , MD, PHD - part II - Preview 1

A confluence of factors will drive the shift to digital pathology.

1min

24 Feb 2020

Rank #3

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Clifford Morris, PhD, Laboratory Medicine 2.0 - Episode 6

Laboratory Medicine 2.0 holds much promise, but we have many challenges to overcome before it is a reality. Will we be able to move away from volume based testing to value based testing? Will we be able to show definitively that patient outcomes and overall levels of health can be improved using laboratory methods? And will we be able to move away from sick care and more towards a system of wellness care?

27mins

29 Jan 2020

Rank #4

Most Popular Podcasts

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Clifford Morris, PhD - Preview 2

"Having specifics is really the whole point of using AI...not to get general trends."

4 Feb 2020

Rank #5

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Roger Klein, MD, JD part ii - Preview 2

"It's actually a good thing from an economics standpoint..." Dr. Roger Klein on whether falling prices can help spur innovation

16 Jan 2020

Rank #6

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RAFAEL ROSENGARTEN, PHD - PREVIEW 3

What role will AI play in the development of new diagnostics?

20 Feb 2020

Rank #7

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Dr. Jill Hagenkord - Preview 2

"Think of the difference we could make in healthcare."

4 Dec 2019

Rank #8

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Roger Klein, MD, JD part ii - Preview 1

“I’m going to have to present a counter view. I think no. These types of tests are going to be commoditized as more providers come into the space.” Roger Klein, MD, JD on if diagnostics providers are going to be able to capture value in the liquid biopsy market

16 Jan 2020

Rank #9

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Roger Klein, MD, JD, part ii, Are we Spiraling to the Bottom? - Episode 3

Are we spiraling to the bottom? Is there any hope for value-based pricing in diagnostics?Roger D. Klein MD, JD, FCAP is a former HHS Advisor to FDA, CMS and CDC, and the immediate past chair of the Association for Molecular Pathology (AMP) Solid Tumors Division. A physician and an attorney, Dr Klein served as an expert and key spokesperson in the lawsuit “Association for Molecular Pathology v. Myriad Genetics, Inc.” in which the U.S. Supreme Court invalidated patents on breast cancer genes. He is a leading authority on public policies related to the implementation of precision medicine.

19mins

7 Jan 2020

Rank #10

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Dr. Jill Hagenkord, Bridging the Gap Between Health Tech and Health Care - Episode 1

Can we bridge the cultural gap between health tech and health care? What happens when "fail fast, fail often " and "move quickly and break things" meets patient care?Dr. Jill Hagenkord, the co-founder of MDisrupt and previous Chief Medical Officer at Complete Genomics, Invitae, 23 and Me and Color Genomics joins us.

28mins

9 Dec 2019

Rank #11

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Dr. Jill Hagenkord - Preview 3

"We're going to have to make it more patient-centric in the very near future."

5 Dec 2019

Rank #12

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Rafael Rosengarten, PhD - Preview 1

We've all heard the hype. But what exactly is AI?

20 Feb 2020

Rank #13

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Julie Eggington, MS, PhD - Preview 2

"Hang on! genetic variants are actually very, very common."

29 Jan 2020

Rank #14

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Julie Eggington, MS, PhD - Preview 3

Variants of Uncertain Significance (VUS) cause tension but really shouldn't.

29 Jan 2020

Rank #15

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Michael Bonham, MD, PhD, CMO of Proscia, The Promise of Digital Pathology - Episode 7

Pathologists have used largely the same technology to make diagnoses since the late 1800's. Will Pathology be able to go fully digital and enter the 21st century? Michael Bonham, MD, PhD, Chief Medical Officer of Proscia, joins us to discuss the promise of digital pathology.

18mins

4 Feb 2020

Rank #16

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Clifford Morris, PhD - Preview 3

"So many lab test are just done...and nothing gets done about them."

4 Feb 2020

Rank #17

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Hannah Mamuszka, Who is the Customer? - Episode 4

Hannah Mamuszka, CEO of Alva10 tells us how cost-based pricing and the commoditization of diagnostic tests has stifled innovation. The promise of value-based pricing, though, is still very much alive. The key, she says, lies in restructuring the relationship between the diagnostics providers and the payors.

29mins

17 Jan 2020

Rank #18

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Michael Bonham MD,PhD, Chief Medical Officer of Proscia - part ii - Have we reached the tipping point? - Episode 9

Michael Bonham MD,PhD, Chief Medical Officer of Proscia is back! Last time we talked about how pathologists are using the same technology – the light microscope – that they have been for the past 150 years. The rate of converting to a fully digital system, particularly in the United States, is abysmally low.With a global shortage of pathologists and regulatory barriers coming down, could we finally be reaching a tipping point? Could #AI be the missing link that will push us over the edge?

19mins

20 Feb 2020

Rank #19

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Julie Eggington, MS, PhD, Center for Genomic Interpretation - Episode 5

We can now test anyone for nearly any genetic mutation or alteration. What could possibly go wrong?Julie Eggington, MS, PhD, co-founder and CEO of Center for Genomic Interpretation joins us this week.

28mins

21 Jan 2020

Rank #20