Cover image of My Instruction Manual

My Instruction Manual

When Keith McArthur got a second chance at life, he was determined not to waste it. After his little sister gave him a life-saving kidney, Keith set out to learn how to be happier and healthier, have ... Read more

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93: The Ethics of Cure with Eli Clare

93: The Ethics of Cure with Eli Clare

Cure is polarizing. For scientists and rare disease parents, it’s seen it as the holy grail. But in disability politics,... Read more

25 May 2020

45mins

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92: Why Cure Is Controversial

92: Why Cure Is Controversial

The notion of curing a rare disease can be controversial. Tom Shakespeare, a bioethicist and disability rights advocate,... Read more

18 May 2020

33mins

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91: Aislinn's Story

91: Aislinn's Story

Siblings of kids with complex medical needs also have complicated lives. An interview with a rare disease sibling and he... Read more

11 May 2020

29mins

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90: Layla's Story

90: Layla's Story

Rare Disease mom Kelly Harris talks about her daughter's GRIN Disorder Diagnosis, her biggest fears for Layla, and why i... Read more

4 May 2020

17mins

Most Popular Podcasts

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89: How CRISPR Will Change the World

89: How CRISPR Will Change the World

Adam Bolt, director of the documentary Human Nature, joins Keith for a conversation about the incredible possibilities a... Read more

27 Apr 2020

28mins

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88: The Good Doctor

88: The Good Doctor

Keith chats with Dr. Ronni Cohn, the geneticist who diagnosed Bryson's Rare Disease. Dr. Ronald (Roni) Cohn is a genetic... Read more

20 Apr 2020

15mins

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87: Pandemic Life

87: Pandemic Life

Pandemic Life sucks. But there are some silver linings. We explore them here. And Keith shares a trailer for his new CBC... Read more

13 Apr 2020

26mins

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86: 8 Life-Changing Lessons

86: 8 Life-Changing Lessons

We all want to live better lives. In this special episode, host Keith McArthur brings back 8 of his favorite guests to a... Read more

13 Jan 2020

25mins

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85: New Year's Resolutions with Jeff Grace

85: New Year's Resolutions with Jeff Grace

Jeff Grace interviews Keith about his book Winning Resolutions and the secrets of successful resolution setting. Jeff is... Read more

30 Dec 2019

1hr 4mins

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84: How To Nail Your New Year's Resolutions with Mike Carruthers

84: How To Nail Your New Year's Resolutions with Mike Carruthers

Mike Carruthers interviews Keith about his book Winning Resolutions and the secrets of successful resolution setting. M... Read more

16 Dec 2019

17mins

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