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This Week in Neuroscience

A podcast about the nervous system.

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Ranked #1

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TWiN 42: Therapeutic effects of psychedelic drugs

TWiN 42: Therapeutic effects of psychedelic drugs

TWiN explains how psychedelic drugs such as LSD, psilocybin, and MDMA, which are being explored for treating a wide rang... Read more

18 Jul 2023

56mins

Ranked #2

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TWiN 41: Alzheimer's and melanin-concentrating hormone

TWiN 41: Alzheimer's and melanin-concentrating hormone

Vivianne explains how early in Alzheimer’s disease, the brain attempts to counteract the increased excitatory drive caus... Read more

20 Jun 2023

1hr 18mins

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Ranked #3

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TWiN 40: Dopamine organizes behavior's syllables

TWiN 40: Dopamine organizes behavior's syllables

Tim takes TWiN through two studies on the role of dopamine: that syllables are natural units of spontaneous behavior use... Read more

11 May 2023

1hr 4mins

Ranked #4

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TWiN 39: Virus-like capsids trigger paraneoplastic disease

TWiN 39: Virus-like capsids trigger paraneoplastic disease

Junjie from Jason’s lab joins TWiN to discuss the observation that the cell gene PNMA2 encodes non-enveloped virus-like ... Read more

28 Apr 2023

52mins

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Ranked #5

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TWiN 38: Bacterial immunity heals sensory neurons

TWiN 38: Bacterial immunity heals sensory neurons

TWiN explains the finding that immunity to commensal bacteria promotes sensory neuron regeneration via the cytokine inte... Read more

27 Mar 2023

1hr 4mins

Ranked #6

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TWiN 37: Microglia at the crossroads

TWiN 37: Microglia at the crossroads

TWiN reviews the field of microgial research, which has advanced in recent decades but is constrained by nomenclature th... Read more

23 Jan 2023

1hr 15mins

Ranked #7

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TWiN 36: Unbearable neurologists

TWiN 36: Unbearable neurologists

TWiN answers listener questions about Alzheimer’s disease, glaucoma and the microbiota, Dravet’s Syndrome, schizophrenia... Read more

3 Jan 2023

1hr 29mins

Ranked #8

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TWiN 35: Neuromodulation in treatment-resistant depression

TWiN 35: Neuromodulation in treatment-resistant depression

Jason and Tim review the use of an implanted chronic deep brain sensing and stimulation device to carry out biomarker-dr... Read more

6 Dec 2022

1hr 9mins

Ranked #9

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TWiN 34: Microglia vital after spinal cord injury

TWiN 34: Microglia vital after spinal cord injury

TWiN explains how central nervous system resident macrophages known as microglia coordinate cellular interactions during... Read more

30 Sep 2022

1hr 9mins

Ranked #10

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TWiN 33: Viruses leaving the brain

TWiN 33: Viruses leaving the brain

TWiN describes how neurotropic viruses leave the brain via meningeal lymphatic vessels located dorsally and basally bene... Read more

31 Aug 2022

58mins

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