DTB podcast

In October's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss wide variation in the use of fibrates and the need for clinicians to consider whether their prescribing of fibrates is up to date and appropriate for their patients. The editors also talk about the evidence for fibrates in primary and secondary prevention of cardiovascular disease, highlight recent changes in the BNF and review a case of severe acute ocular hypertension following pulsed methylprednisolone.Read the full October issue: https://dtb.bmj.com/content/57/10

In September's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the roll out of social prescribing across the NHS in England. The editors also talk about a new formulation of naloxone for emergency treatment of opioid overdose in adults and review a case that involved successful thrombolysis for acute ischaemic stroke after using idarucizumab to reverse the action of dabigatran etexilate.To read any of the September articles, please visit: https://dtb.bmj.com/content/57/9.

In August's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss pre-eclampsia and the benefit of measuring the level of placental growth factor to help speed up diagnosis. The editors also talk about the challenge of communicating evidence to patients and review a case of complex encephalopathy arising from the combination of opioids and gabapentin.Read the full issue: https://dtb.bmj.com/content/57/8.

As the UK continues to be in lockdown because of the coronavirus pandemic, this podcast only features David Phizackerley, DTB's Deputy Editor, who provides a brief overview of the May issue of DTB. This includes an editorial that discusses the challenges facing clinicians in involving children and young people in decisions about their healthcare; a summary of the EMA's advice on the use of ibuprofen in people who have Covid-19; and an article on the development of shared care prescribing guidelines over the last 30 years.The main article looks at the benefits and harms of using potassium permanganate for wound care, and the issue finishes with a case report of hypersensitivity pneumonitis associated with sertraline.Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (podcasts.apple.com/gb/podcast/dtb-…ast/id307773309). Thank you for listening. Go well and stay well.

In April's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss lung volume reduction surgery for patients with emphysema-predominant COPD (https://dtb.bmj.com/content/58/4/50). They highlight the results of a trial of low-dose amitriptyline for chronic low back pain (https://dtb.bmj.com/content/58/4/53), discuss the use of depot triamcinolone injection for hay fever (https://dtb.bmj.com/content/58/4/57), and talk about a case in which dapagliflozin was thought to have caused euglycaemic diabetic ketoacidosis (https://dtb.bmj.com/content/58/4/60). If you enjoy the DTB podcast, please subscribe to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.Read the full April issue: dtb.bmj.com/content/58/4

In March's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the decision to extend the license for dapagliflozin 5 mg tablets to include use by people with type 1 diabetes and highlight concerns over the incidence of diabetic ketoacidosis. They review an article on managing asthma before and during pregnancy and talk about a case of partial nephrogenic diabetes insipidus associated with lithium therapy.Read the full March issue: dtb.bmj.com/content/58/3 If you enjoy the podcast, please subscribe to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment at https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309. Thank you for listening.

In February's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) consider the impact of conflicts of interest and highlight the need to establish comprehensive registers of conflicts of interest for healthcare professionals, healthcare providers and patient support groups. They briefly review an article on melatonin for jet lag (a longer version is available here: https://soundcloud.com/bmjpodcasts/melatonin-for-jet-lag?in=bmjpodcasts/sets/dtb-podcast), discuss a review of the management of nocturnal enuresis and highlight a report of a possible case of statin-induced delayed rhabdomyolysis.Read the full February issue: https://dtb.bmj.com/content/58/2 If you enjoy the podcast, please subscribe to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment at https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309. Thank you for listening.

In this podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss a formulation of melatonin that has been licensed in the UK for the management of jet lag. The editors review the evidence for its effectiveness in reducing symptoms of jet lag and consider whether it should be available from the National Health Service. Read the article here: http://dx.doi.org/10.1136/dtb.2019.000074.Please subscribe to the DTB Podcast to get episodes automatically downloaded to your phone and computer every month. If you enjoy the show, please leave us a review or a comment at podcasts.apple.com/gb/podcast/dtb-…ast/id307773309. Thank you for listening!

In January's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) consider the burden of overprescribing and discuss how to tackle some of the barriers to deprescribing (https://dtb.bmj.com/content/58/1/2). They also review an article on the place of aspirin for primary prevention of cardiovascular disease (https://dtb.bmj.com/content/58/1/3), highlight an article on prescribing for pregnancy for women with mental health issues (https://dtb.bmj.com/content/58/1/8), and discuss a case report of sitagliptin-induced seronegative rheumatoid arthritis (https://dtb.bmj.com/content/58/1/12).Please subscribe to get episodes automatically downloaded to your phone and computer every month. If you enjoy the podcast, please leave us a review or a comment at https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309. Thank you for listening.

In December's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) consider the results of a recent study that assessed the effect of a combination pill containing aspirin, atorvastatin, enalapril and hydrochlorothiazide on major cardiovascular outcomes - https://dtb.bmj.com/content/57/12/178. The editors discuss prasterone, a newly introduced treatment for vulvar and vaginal atrophy - https://dtb.bmj.com/content/57/12/185. They also review a case report of retrograde ejaculation associated with quetiapine and treatment with low-dose imipramine - https://dtb.bmj.com/content/57/12/189.Read the December issue on the DTB website: https://dtb.bmj.com/content/57/12.

In November's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss whether primary care targets for managing blood pressure control in older people are achievable or desirable. The editors also introduce the first of a series of articles that consider therapeutic challenges when preparing for pregnancy and highlight some of the key issues that should be considered for all women as part of pre-pregnancy care. They also review a case report of apixaban-induced acute interstitial nephritis.Read the full November issue: https://dtb.bmj.com/content/57/11

In June's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) consider the European Medicines Agency's decision to amend the licence for omega-3 fatty acid medicines so that they will no longer be authorised for secondary prevention after myocardial infarction. The editors also review ospemifene, a new medicine for the management of vulvar and vaginal atrophy and discuss a case of delusional infestation in the treatment of ADHD with atomoxetine.Read the full issue: https://dtb.bmj.com/content/57/6.

In May's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) highlight some of the opportunities for drugs and therapeutics in the new GP contract for England. The editors also talk about the management of chronic cough and discuss a case of acute liver failure associated with a short course of nitrofuantoin.Read the issue online: https://dtb.bmj.com/content/57/5.

In April's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) highlight some of the challenges of prescribing direct acting oral anticoagulant (DOAC) drugs for people with renal impairment. The editors also talk about the use of saline nasal irrigation and discuss central sensitisation syndrome.Read the issue online: https://dtb.bmj.com/content/57/4.

In March's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) get excited about the impact that the results of the Direct study could have on the management of type 2 diabetes. The editors also discuss the combination of doxylamine and pyridoxine for the treatment of nausea and vomiting in pregnancy and consider the role of primary care in supporting patients who are taking clozapine.Read the full issue: https://dtb.bmj.com/content/57/3.

In February's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the use of inhaled corticosteroids in the management of COPD (https://dtb.bmj.com/content/57/2/18). The editors also consider subclinical hypothyroidism in pregnancy (https://dtb.bmj.com/content/57/2/22) and discuss Gilbert’s syndrome (https://dtb.bmj.com/content/57/2/27).Read the full issue: https://dtb.bmj.com/content/57/2

In January's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss whether intravenous antibiotics are always needed. The editors also consider the challenge of stopping antipsychotic drug treatment in people with intellectual disability and review a case of angioedema of the small bowel caused by lisinopril.Read the issue: dtb.bmj.com/content/57/1.

In December's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the conditional authorisation process for medicines and the need for clearer labelling of medicines that have been through this approval processes. The editors also consider common sources of information on medicines for patients and review a case of interstitial lung disease associated with adalimumab.Read the issue: https://dtb.bmj.com/content/56/12.

In October's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the place of population screening for atrial fibrillation and the need for more evidence to support a change in national policy (https://dtb.bmj.com/content/56/10/112). The editors also consider problems associated with long-term opioid use in the management of chronic pain (https://dtb.bmj.com/content/56/10/118). Please watch the video about Michael's moving story on this subject at dtb.bmj.com.The launch of slidenafil as an over-the-counter pharmacy medicine (https://dtb.bmj.com/content/56/10/123) is also discussed.Read the latest from the reinvented Drug and Therapeutics Bulletin here: dtb.bmj.com.

In September's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) highlight some of the changes to DTB that have taken place this month and discuss the background and rationale to these changes. Read this month's editorial: https://dtb.bmj.com/content/56/9/98.The editors also consider the place for monitored dosage systems (https://dtb.bmj.com/content/56/9/102) and discuss the evidence for using labetalol as a first-line treatment option for hypertension in pregnancy (https://dtb.bmj.com/content/56/9/107).Meet the new DTB here: https://dtb.bmj.com/content/56/9.