How To Halt Cancer at “Stage NEGATIVE 1” - Azra Raza
Today if you’re diagnosed with Stage 3 or Stage 4 cancer, your chances of surviving are no better than if you lived in 1930. But your chances are 100 times better when catch it early.What if you could catch cancer SUPER early - years before any obvious indication of a problem?And what if you could then solve the problem at its roots so it never recurs at all?Azra Raza is an oncologist at Colombia University and author of The First Cell: The Human Costs of Pursuing Cancer to the Last. Here she describes the First Cell Project. This is a collaboration with world class cancer researchers who have discovered how to identify “Giant Cells” that PREDATE and predict the generation of tumors YEARS in advance.You’ll be privy to the incredibly moving story of Andrew, her daughter’s best friend who died of brain cancer at age 24… and the systemic problems that continue to plague the cancer field and repeat the tragedy of Andrew. Here we discuss why only outsiders will solve these problems.WEBSITE LINKS: www.azraraza.com www.firstcellcenter.comBe sure and watch my previous interview with Azra Raza at www.evo2.org/azra - it’s a barn burner and provides important background that gives rich context to this new discussion. See acast.com/privacy for privacy and opt-out information.
Dr. Azra Raza - Anticipate, Find, And Destroy The FIRST Cancer Cell; STOP The Disease In Its Tracks
Progress, Potential, and Possibilities
As we approach the end of 2020, according to the U.S. National Cancer Institute (NCI), we have had approximately 1,806,590 new cases of cancer diagnosed in the United States, with 606,520 deaths. Cancer continues to be the leading causes of death worldwide. In 2018, there were 18.1 million new cases and 9.5 million cancer-related deaths worldwide. By 2040, the number of new cancer cases per year is expected to rise to 29.5 million and the number of cancer-related deaths to 16.4 million. Dr. Azra Raza, MD, is the Chan Soon-Shiong Professor of Medicine, in the Department of Medicine, Division of Hematology / Oncology, and Director of the Myelodysplastic Syndrome (MDS) Center, at the Columbia University Medical Center. Previously, Dr. Raza was the Chief of Hematology-Oncology and the Gladys Smith Martin Professor of Oncology at the University of Massachusetts. Dr. Raza is an international authority on pre-leukemia / MDS, and acute leukemia, and is both a physician and scientist who divides her time equally between caring for patients and supervising a state-of-the-art basic research lab which is well-funded by multiple large grants. Dr. Raza started collecting blood and marrow samples on her patients in 1984 and now her Tissue Bank, the largest and oldest in the country with over 60,000 samples, is considered a unique national treasure. Dr. Raza has published her original clinical and basic research comprising over 300 peer-reviewed manuscripts in high profile journals like Nature, New England Journal of Medicine, Cell, Molecular Cell, Cancer Research, Blood, Leukemia. She has published over 1,000 abstracts, dozens of book chapters and edited a book devoted to MDS, entitled "Myelodysplastic Syndromes & Secondary Acute Myelogenous Leukemia: Directions for the New Millennium". Dr. Raza is the recipient of numerous awards including The Hope Award in Cancer Research 2012 (shared with the Nobel Laureate Dr. Elizabeth Blackburn). She was named as one of the 100 Women Who Matter by Newsweek Pakistan. Dr. Raza is a member of the Founder Group designing Breakthrough Developments in Science and Technology with President Bill Clinton, and was involved with Vice President Joe Biden to discuss the Cancer Moonshot initiative. Dr. Raza is the author of the recently published book "The First Cell: And the Human Costs of Pursuing Cancer to the Last". In addition to her scientific accomplishments, Dr. Raza is a dedicated reader of Urdu literature, and co-authored a book on the poems of the 19th century Indian poet Ghalib, entitled "Ghalib: Epistemologies of Elegance".
For more about Azra, see her website: https://azraraza.com/The First Cell: And the Human Costs of Pursuing Cancer to the Last is available here: https://www.amazon.com/First-Cell-Human-Pursuing-Cancer/dp/1541699521Her book with Sara Suleri Goodyear, Ghalib and the Epistemologies of Elegance is available here:https://www.goodreads.com/book/show/7502220-ghalibHer physician profile can be found here:https://cancer.columbia.edu/azra-raza-mdFollow Azra on Twitter: @AzraRazaMDFurther ReferencesGeorge Eliot, Middlemarch: A Story of Provincial Life (1871–2)The complete poems of Emily Dickinson (first published 1890) are available online here: https://www.gutenberg.org/files/12242/12242-h/12242-h.htm Rebecca Skloot, The Immortal Life of Henrietta Lacks (2011)Oscar Wilde, The Ballad of Reading Gaol (1897)Samuel Johnson, The Rambler (1750):https://www.johnsonessays.com/category/the-rambler/The Crown, “Aberfan” (BBC)Siddhartha Mukherjee, The Gene (2016) and The Emperor of All Maladies (2010)TimestampsBeginning: introduction and Azra reads from The First Cell6:15 How Azra became interested in medicine and in oncology in particular14:32 The evolutionary model of cancer’s development in the body23:50 Cancer and critical systems; the MIST of aging31:54 Peto’s paradox41:45 Why cell culture and animal testing methods don’t work47:41 The immune system, CAR-T treatments, B cells, checkpoint inhibitors1:00:50 Azra’s personalised approach and how she came to develop it1:05:59 New, more radical earlier detection methods 1:21:37 The oncology think tank1:22:48 Monitoring technologies1:29:32 Azra’s relationship with literature
Leukemia and Questioning Advancements in Cancer Research and Treatment (Interview with Dr. Azra Raza, the Chan Soon-Shiong Professor of Medicine and Director of the MDS Center at Colombia University)
🟦Welcome to SciSection! Joining us today is our special guest Dr. Azra Raza; a physician-scientist, Chan Soon-Shiong Professor of Medicine and Director of the MDS Center at Colombia University, and creator of the largest tissue repository in the US! We'll be learning about tissue repository, leukemia, and so much more 👀🔬! 🟨Journalist: Anna Yang 🟦Don’t forget to follow us on Instagram, like us on Facebook, and catch us live on the radio on CFMU 93.3 FM Wednesdays at 6pm. For more info and SciSection content, check us out on our website! 🟨Curious about a topic? Want to hear us talk about it? Any feedback? Let us know by sending an email to firstname.lastname@example.org!
#121 - Azra Raza, M.D.: Why we're losing the war on cancer
The Peter Attia Drive
Azra Raza is a physician, scientist, author, and outspoken advocate for reconfiguring the current model of research in cancer. In this episode, Azra discusses the content of her book, The First Cell, which takes a critical look at the outdated models being used to study cancer resulting in a lack of progress in survival rates for cancer patients. Azra offers a solution which focuses on early detection and prevention, and she concludes with an optimistic outlook for the future of cancer research. We discuss: Azra’s upbringing, interest in oncology, and the basis for writing her book [3:30]; The lack of progress in cancer treatment over the decades [18:45]; What is holding the oncology field back? [33:15]; Do the purported advances in oncology reflect the billions of dollars spent on cancer research? [40:00]; Economics of new cancer drugs—how small increases in survival come with staggering financial burdens [47:00]; How good intentions can still lead to misaligned incentives and a broken system [1:03:00]; Why 95% of new cancer drugs fail—a critical review of the cancer research model [1:11:15]; Early detection and prevention—a potential solution to the cancer problem [1:22:30]; Coping with the loss of her husband to cancer [1:46:00]; Azra’s optimistic view of the future [1:49:30]; and More. Learn more: https://peterattiamd.com/ Show notes page for this episode: https://peterattiamd.com/azraraza Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Connect with Peter on Facebook | Twitter | Instagram.
Prof. Azra Raza, Professor of Medicine and Director of the MDS Center at Columbia University
Scientific Sense ®
Cancer - why have we failed, and how can we get better? The quest to find and destroy the first cell to minimize human strife. Prof. Azra Raza is a Professor of Medicine and Director of the MDS (Myelodysplastic Syndrome) Center at Columbia University. She is a practicing oncologist seeing 30-40 cancer patients weekly. She worked with President Clinton designing Breakthrough Developments in Science and Technology and with Vice President Joe Biden for the Cancer Moonshot initiative. Her latest book, THE FIRST CELL: And the human costs of pursuing cancer to the last was published in October 2019.--- Send in a voice message: https://anchor.fm/scientificsense/messageSupport this podcast: https://anchor.fm/scientificsense/support
Slash, Poison, Burn: How We Treat Cancer, and How We Should—Azra Raza, MD—Myelodysplastic Syndromes (MDS) Center at Columbia University in New York
Finding Genius Podcast
Azra Raza is the Chan Soon-Shiong Professor of Medicine and Director of the Myelodysplastic Syndromes (MDS) Center at Columbia University in New York, a practicing oncologist, and author of The First Cell: And the Human Costs of Pursuing Cancer to the Last. She joins the show to discuss several incredibly important topics, including the following: Why there is a significant problem with the use of mice as models for cancer research and what needs to be done in order to really understand the earliest footprints of cancer in humans How Dr. Raza is trying to overcome the financial barriers to the research necessary for cancer prevention and early detection Why a complete paradigm shift is needed within the cancer industry “Today…we are curing 68% of the cancers, and that’s great, but what are we curing them with? Slash, poison, burn: surgery, chemotherapy, radiation…the same treatments we were using…with a few rare exceptions…it is shocking that in this day and age of such advanced technology we are using such paleolithic caveman treatments...” says Dr. Raza, who has devoted over 30 years of her life to the early detection and prevention of cancer while working firsthand with countless cancer patients. She continues by explaining that these treatments (surgery, chemotherapy, and radiation) were initially given as stop-gap measures, and despite the efforts of thousands of scientists over the course of the last several decades, a more successful treatment has not been developed. Why? According to Dr. Raza, a big part of the answer has to do with the fact that cancer is heterogeneous; it’s a moving target that’s continually evolving and picking up new mutations. So, what’s the solution? In Dr. Raza’s view, the solution is early detection and prevention of the development of cancer, rather than attempts to treat it once it’s already advanced, and she emphasizes the need to use every available resource to this end, including genomics, metabolomics, proteomics, and transcriptomics. She explains the financial burden of pursuing this research pathway, how she’s trying to overcome it, and so much more. “On a daily basis I am seeing patients, and it is their stories that are the motivation for me…I am looking at everything through the prism of human anguish…to separate human suffering and pain from the need to find the answers is criminal, because the motivation has to be…to reduce human suffering.” Tune in to hear the full conversation, and visit https://azraraza.com/ to learn more about Dr. Raza’s mission.
Dr. Azra Raza on the Human Costs of Pursuing Cancer
Just the Right Book with Roxanne Coady
According to the NIH, there has been a seventy-percent decline annually in the death rate from cardiovascular disease in the last fifty years and a one percent decline annually in the death rate from cancer over the last fifty years. How can this be when we keep hearing about great new drug discoveries and immunotherapy advances? And if true, isn't there another way to approach the nightmare that is cancer? This week on Just the Right Book, Dr. Azra Raza join Roxanne Coady to discuss her latest book, The First Cell: And the Human Costs of Pursuing Cancer to the Last, out now from Basic Books. Learn more about your ad choices. Visit megaphone.fm/adchoices
The Soul of Enterprise: Business in the Knowledge Economy
We are honored to have Dr. Azra Raza on the show. She is a sought after speaker in scientific circles and the recipient of numerous awards including The Hope Award in Cancer Research 2012 and named as one of the 100 Women Who Matter by Newsweek Pakistan. She is a member of the Founder Group designing Breakthrough Developments in Science and Technology with President Bill Clinton and met with Vice President Joe Biden to discuss the Cancer Moonshot initiative in 2015. She is the author of The First Cell: And the human costs of pursuing cancer’s last published by Basic Books, October 2019. Dr. Raza believes that the best way to “tame the savageness of man and make gentle the life of this world” is by promoting and publicizing the achievements of humanity in science, art, and literature. She was married to the late Harvey D. Preisler, Director, Rush University Cancer Center in Chicago and has a daughter Sheherzad Raza Preisler who also lives in New York.
Author and oncologist Azra Raza talks about her book The First Cell with EconTalk host Russ Roberts. Raza argues that we have made little progress in fighting cancer over the last 50 years. The tools available to oncologists haven't changed much--the bulk of the progress that has been made has been through earlier and earlier detection rather than more effective or compassionate treatment options. Raza wants to see a different approach from the current strategy of marginal improvements on narrowly defined problems at the cellular level. Instead, she suggests an alternative approach that might better take account of the complexity of human beings and the way that cancer morphs and spreads differently across people and even within individuals. The conversation includes the challenges of dealing with dying patients, the importance of listening, and the bittersweet nature of our mortality.