Marc Semigran Renovacor's guest appearances

Marc Semigran Renovacor

Empowered Patient Podcast

Mark Allen

David Katz

Rosalind Picard

David Solomon

Matt Murphy

Robin Smith

Thomas Cowan

Greg Miller

Travis Mickle

Justin Miller

Sean Tucker

Matt Wilson

Chris Young

Jim Martin

Robin Zander

OwlTail

Dr. Marc Semigran is the Chief Medical Officer of Renovacor and shines a light on BAG3-associated cardiomyopathy and the cardiac gene therapy in development to treat this rare genetic disease. Marc explains, "So, what we are focusing on are patients who have a genetic or familial origin of their dilated cardiomyopathy. Our first target is a gene described as BAG3, which is an important protein within the cardiac muscle cells. And some patients with heart failure have the heart failure because the gene that they have is mutated and is not able to fully express a functional protein." "We are studying our lead asset, which is REN-001, a modified virus that we believe will specifically target the heart. This will insert into the cardiac muscle cells a good copy of the BAG3 gene, which can then be expressed and allow those cardiac muscle cells to begin to function normally." #Renovacor #GeneTherapy #DilatedCardiomyopathy #DCM #BAG3 #RareDisease Renovacor.com Download the transcript here

Dr. Marc Semigran is the Chief Medical Officer of Renovacor and shines a light on BAG3-associated cardiomyopathy and the cardiac gene therapy in development to treat this rare genetic disease. Marc explains, "So, what we are focusing on are patients who have a genetic or familial origin of their dilated cardiomyopathy. Our first target is a gene described as BAG3, which is an important protein within the cardiac muscle cells. And some patients with heart failure have the heart failure because the gene that they have is mutated and is not able to fully express a functional protein." "We are studying our lead asset, which is REN-001, a modified virus that we believe will specifically target the heart. This will insert into the cardiac muscle cells a good copy of the BAG3 gene, which can then be expressed and allow those cardiac muscle cells to begin to function normally." #Renovacor #GeneTherapy #DilatedCardiomyopathy #DCM #BAG3 #RareDisease <a href="http://renovacor.com" rel="noopener nofollow" target="_blank">Renovacor.com</a> <a href="http://empoweredpatientradio.com/targeting-underlying-gene-mutation-causing-dilated-cardiomyopathy-with-dr-marc-semigran-renovacor-transcript" rel="noopener nofollow" target="_blank">Download the transcript here</a>

Targeting Underlying Gene Mutation Causing Dilated Cardiomyopathy with Dr. Marc Semigran Renovacor