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Richard Peto

7 Podcast Episodes

Latest 24 Jul 2021 | Updated Daily

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Richard Peto

Discovery

When Sir Richard Peto began work with the late Richard Doll fifty years ago, the UK had the worst death rates from smoking in the world. Smoking was the cause of more than half of all premature deaths of British men. The fact that this country now boasts the biggest decrease in tobacco-linked mortality is in no doubt partly due to Doll and Peto's thirty year collaboration.Professor of Medical Statistics and Epidemiology at the University of Oxford and until last year co-director of the Clinical Trial Service Unit with Professor Sir Rory Collins, Richard Peto pioneered "big data", setting up enormous randomised clinical trials and then, in a novel approach, combining results in what became known as meta-analyses, amassing unequivocal evidence about how early death could be avoided. He showed how asprin could prevent heart attacks and how the oestrogen-blocking drug tamoxifen really did affect survival rates for breast cancer patients.Results on paper saves lives in the real world, he says, and he's famous for catchphrases like: "death in old age is inevitable, but death before old age is not" and "you can avoid more deaths by a moderate reduction of a big cause, than by a big reduction in a small cause" as well as "take the big numbers seriously".One of the world's leading epidemiologists, Richard Peto's landmark study with Alan Lopez at the World Health Organisation predicted that a billion people would die from diseases associated with tobacco this century, compared to a hundred million killed by tobacco in the 20th century. The chilling message galvanised governments around the world to adopt anti-smoking policies. And Professor Peto's studies about smoking cessation ("smoking kills, stopping works") provided the public health evidence needed to encourage smokers that, however long they had smoked for, it was always worth quitting.

27mins

5 Aug 2019

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Richard Peto on why smoking kills but quitting saves lives

The Life Scientific

When Sir Richard Peto began work with the late Richard Doll fifty years ago, the UK had the worst death rates from smoking in the world. Smoking was the cause of more than half of all premature deaths of British men. The fact that this country now boasts the biggest decrease in tobacco-linked mortality is in no doubt partly due to Doll and Peto's thirty year collaboration.Professor of Medical Statistics and Epidemiology at the University of Oxford and until last year co-director of the Clinical Trial Service Unit with Professor Sir Rory Collins, Richard Peto pioneered "big data", setting up enormous randomised clinical trials and then, in a novel approach, combining results in what became known as meta-analyses, amassing unequivocal evidence about how early death could be avoided. He showed how asprin could prevent heart attacks and how the oestrogen-blocking drug tamoxifen really did affect survival rates for breast cancer patients.Results on paper saves lives in the real world, he says, and he's famous for catchphrases like: "death in old age is inevitable, but death before old age is not" and "you can avoid more deaths by a moderate reduction of a big cause, than by a big reduction in a small cause" as well as "take the big numbers seriously".One of the world's leading epidemiologists, Richard Peto's landmark study with Alan Lopez at the World Health Organisation predicted that a billion people would die from diseases associated with tobacco this century, compared to a hundred million killed by tobacco in the 20th century. The chilling message galvanised governments around the world to adopt anti-smoking policies. And Professor Peto's studies about smoking cessation ("smoking kills, stopping works") provided the public health evidence needed to encourage smokers that, however long they had smoked for, it was always worth quitting. Producer: Fiona Hill

29mins

9 Apr 2019

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Halving cancer mortality - Prof Richard Peto

IARC 2016

Prof Peto speaks with ecancertv at IARC 2016 about the means by which he believes cancer diagnoses can be halved.He outlines the necessary steps of tackling the social and environmental causes of cancer, specifically smoking and infectious diseases.Looking at global cancer incidences, Prof Peto highlights changing attitudes to anti-smoking and vaccination campaigns, new treatment or detection methods, and the management of cancer in developing economies.

13mins

31 Jul 2016

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BCU1 2013 | Interview with Sir Richard Peto

Breast Cancer Update

Conversations with Oncology Investigators. Bridging the Gap between Research and Patient Care. Interview with Sir Richard Peto conducted by Neil Love, MD. Produced by Research To Practice.

38mins

15 May 2013

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Analysis of thirty years of clinical trial data: Prof Richard Peto - Clinical Trial Service Unit, Oxford University

8th European Breast Cancer Conference (EBCC-8)

Prof Richard Peto discusses the analysis of thirty years of treatment data, compiled by the University of Oxford. Every five years trial data from all over the world was analysed to give a more definite answer on what treatments have the most substantial effects. The discussion includes analysis of the effects of tamoxifen, chemotherapy and the expense of treatment and screening.

11mins

28 May 2012

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Debate on the success of breast cancer screening programmes: Prof Richard Peto - Clinical Trial Service Unit, Oxford University

8th European Breast Cancer Conference (EBCC-8)

Prof Richard Peto discusses the controversy behind screening for early stage breast cancer at the 8th European Breast Cancer Conference with ecancer Managing Editor Prof Gordon McVie. Prof Peto is involved in a meta-analysis study of all previous trials involving breast cancer and early stage breast cancer screening in order to provide a firm conclusion on the mortality rate with and without screening programs.

10mins

28 May 2012

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BCU2 2008 | Interview with Sir Richard Peto, FRS

Breast Cancer Update

BreastCancerUpdate.com – Conversations with Oncology Investigators. Bridging the Gap between Research and Patient Care. Interviews conducted by Neil Love, MD. Produced by Research To Practice.

24mins

20 Mar 2008