Andrea Califano's guest appearances

Andrea Califano

People Behind the Science Podcast - Stories from Scientists about Science, Life, Research, and Science Careers

WIN 2016

Columbia Invents

Michael Levin

Ayanna Howard

Sarah Bergbreiter

Lawrence Krauss

Nathan Smith

Katie Mack

Adam Gazzaley

Andrew Friedman

Jo Dunkley

Brian Keating

Paul Steinhardt

Chris Barrett

Richard Jefferson

Ryan Martin

David Berman

OwlTail

Dr. Andrea Califano is the Chair of Columbia's Department of Systems Biology and co-founder of DarwinHealth. He speaks about how systems biology targets the body's master regulators, his experience launching DarwinHealth in New York, how he's working with big biopharma to identify known but overlooked compounds that might impact cancer, and how the culture of entrepreneurship at Columbia has changed since he joined. 

Dr. Andrea Califano is the Chair of Columbia's Department of Systems Biology and co-founder of DarwinHealth. He speaks about how systems biology targets the body's master regulators, his experience launching DarwinHealth in New York, how he's working with big biopharma to identify known but overlooked compounds that might impact cancer, and how the culture of entrepreneurship at Columbia has changed since he joined.

Dr. Andrea Califano is the Clyde and Helen Wu Professor of Chemical Systems Biology in the Departments of Systems Biology, Biochemistry &amp; Molecular Biophysics, and Biomedical Informatics at Columbia University. He is Founding Chair of the Department of Systems Biology, Director of the JP Sulzberger Columbia Genome Center, and Associate Director for Bioinformatics of the Herbert Irving Comprehensive Cancer Center. In the lab, Andrea is trying to develop what we can think of as a blueprint or assembly manual for cells. He is using genetic and genomic information to reconstruct models of regulatory systems in normal cells and cells in disease states. They are learning about the proteins that regulate cellular changes in diseases like cancer and neurodegenerative disorders. Andrea and his family enjoy family outings to the botanical gardens, the zoo, and musical events. He also spends his down time playing tennis, skiing, watching movies, and reading. He completed his doctoral studies in physics at the University of Florence in Italy and his postdoctoral studies at MIT. Afterward, Andrea worked at the IBM TJ Watson Research Center, and he subsequently became Program Director of the IBM Computational Biology Center. In 2000, Andrea co-founded First Genetic Trust, Inc and founded another company called Therasys in 2008 before joining the faculty where he is today at Columbia University. Andrea is with us today to tell us all about his journey through life and science.

Dr. Andrea Califano is the Clyde and Helen Wu Professor of Chemical Systems Biology in the Departments of Systems Biology, Biochemistry &amp; Molecular Biophysics, and Biomedical Informatics at Columbia University. He is Founding Chair of the Department of Systems Biology, Director of the JP Sulzberger Columbia Genome Center, and Associate Director for Bioinformatics of the Herbert Irving Comprehensive Cancer Center. In the lab, Andrea is trying to develop what we can think of as a blueprint or assembly manual for cells. He is using genetic and genomic information to reconstruct models of regulatory systems in normal cells and cells in disease states. They are learning about the proteins that regulate cellular changes in diseases like cancer and neurodegenerative disorders. Andrea and his family enjoy family outings to the botanical gardens, the zoo, and musical events. He also spends his down time playing tennis, skiing, watching movies, and reading. He completed his doctoral studies in physics at the University of Florence in Italy and his postdoctoral studies at MIT. Afterward, Andrea worked at the IBM TJ Watson Research Center, and he subsequently became Program Director of the IBM Computational Biology Center. In 2000, Andrea co-founded First Genetic Trust, Inc and founded another company called Therasys in 2008 before joining the faculty where he is today at Columbia University. Andrea is with us today to tell us all about his journey through life and science.

611: Translating Gene Expression Experiments into Therapies for Human Disease - Dr. Andrea Califano

Prof Califano meets with ecancertv at WIN 2016 to discuss results from a recent trial in which aberrant protein activity in patient samples was algorithmically linked to disease progression.The algorithm, VIPER, and protein-reporting Oncotarget tests can reveal protein activity linked to cancer without any apparent genomic mutation. Prof Califano describes the potential advantages of pursuing these proteins as targets where is no actionable mutation, with upcoming studies to report on patient outcomes.He also reports on Oncotreat, which is revealing regulation and conservation of DNA master regulators within cancer cells as a possible upstream target of many oncogenes.

Prof Califano meets with ecancertv at WIN 2016 to discuss results from a recent trial in which aberrant protein activity in patient samples was algorithmically linked to disease progression. The algorithm, VIPER, and protein-reporting Oncotarget tests can reveal protein activity linked to cancer without any apparent genomic mutation. Prof Califano describes the potential advantages of pursuing these proteins as targets where is no actionable mutation, with upcoming studies to report on patient outcomes. He also reports on Oncotreat, which is revealing regulation and conservation of DNA master regulators within cancer cells as a possible upstream target of many oncogenes.