Christopher Reinkemeier's guest appearances

Christopher Reinkemeier

Finding Genius Podcast

FutureTech Podcast

Laura Potterat

Marc Guell

Paul Turner

Jan Vijg

Eleftherios Mylonakis

Cory Kidd

Charles C.J

Helius Medical Technologies

Patrick McKeown

Michael G. Surette

Katelyn Parsons

John Tucker

Jake Kushner

Erik Gunther

Kim Kush

OwlTail

Johannes Gutenberg

Christopher Reinkemeier is a Ph.D. student at the Institute of Molecular Biology at Johannes Gutenberg University of Mainz, where he has been working on the development of a synthetic organelle that can be inserted in living cells and translate one mRNA (messenger RNA) to produce a specifically modified protein. The mechanism is based on genetic code expansion, which is a technique that’s been around for many years and involves artificially changing units of genetic code to encode certain amino acids. Reinkemeier explains that their organelle allows for this process of modification to occur in only one mRNA, leading to the production of only one, very specifically modified type of protein. The fact that their organelle can carry out translation is evidence that synthetic molecules are capable of carrying out complex tasks—one of the most complex tasks a cell does, in fact. In the body, the task of translation requires the recruitment of hundreds of organic molecules that work together to create a protein, but this synthetic organelle requires just five components which recruit all of the other molecules necessary for translation in the cell. Reinkemeier discusses the ins and outs of this technology, the principle of phase separation, different types of organelles, possible applications of their organelle in medicine, and their long-term goals with this research and development. 

Christopher Reinkemeier is a Ph.D. student at the Institute of Molecular Biology at Johannes Gutenberg University of Mainz, where he has been working on the development of a synthetic organelle that can be inserted in living cells and translate one mRNA (messenger RNA) to produce a specifically modified protein. The mechanism is based on genetic code expansion, which is a technique that’s been around for many years and involves artificially changing units of genetic code to encode certain amino acids. Reinkemeier explains that their organelle allows for this process of modification to occur in only one mRNA, leading to the production of only one, very specifically modified type of protein. The fact that their organelle can carry out translation is evidence that synthetic molecules are capable of carrying out complex tasks—one of the most complex tasks a cell does, in fact. In the body, the task of translation requires the recruitment of hundreds of organic molecules that work together to create a protein, but this synthetic organelle requires just five components which recruit all of the other molecules necessary for translation in the cell. Reinkemeier discusses the ins and outs of this technology, the principle of phase separation, different types of organelles, possible applications of their organelle in medicine, and their long-term goals with this research and development.

Targeted Protein Modifications Using a Synthetic Organelle—Christopher Reinkemeier—Institute of Molecular Biology, Johannes Gutenberg University of Mainz

At the Institute of Molecular Biology at Johannes Gutenberg University of Mainz, Christopher Reinkemeier is a Ph.D. student who’s involved with a project that’s providing breakthrough evidence of the ability of synthetic organelles to carry out complex tasks in living cells. How complex? One of the most complex and important processes that cells carry out: translation or the synthesis of proteins. In the body, translation involves hundreds of organic molecules, but the synthetic organelle Reinkemeier has helped to develop requires just five components, which, once in a living cell, recruit all of the other necessary components of translation.  Reinkemeier provides an in-depth discussion about the science behind what they’ve created, and the significance of the fact that it’s capable of modifying one messenger RNA (mRNA) for the production of one, specifically modified protein. Tune in for all the details.

At the Institute of Molecular Biology at Johannes Gutenberg University of Mainz, Christopher Reinkemeier is a Ph.D. student who’s involved with a project that’s providing breakthrough evidence of the ability of synthetic organelles to carry out complex tasks in living cells. How complex? One of the most complex and important processes that cells carry out: translation or the synthesis of proteins. In the body, translation involves hundreds of organic molecules, but the synthetic organelle Reinkemeier has helped to develop requires just five components, which, once in a living cell, recruit all of the other necessary components of translation.  Reinkemeier provides an in-depth discussion about the science behind what they’ve created, and the significance of the fact that it’s capable of modifying one messenger RNA (mRNA) for the production of one, specifically modified protein. Tune in for all the details.

Synthetic Organelle Accomplishing One of the Cell’s Most Complex Tasks—Christopher Reinkemeier—Institute of Molecular Biology, Johannes Gutenberg University of Mainz